Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 7/20 | 0.49 |
| ▸ | DRD2 | P14416 | 6/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857980 | 0.92 | DRD4 (0.47) | DRD4DRD2SIGMAR1HDAC3HDAC4 | |
| SCHEMBL2854763 | 0.87 | DRD4 (0.50) | DRD4DRD2SIGMAR1HDAC3HDAC4 | |
| SCHEMBL2856452 | 0.86 | DRD4 (0.47) | DRD4DRD2SIGMAR1HDAC3HDAC4 | |
| SCHEMBL2859595 | 0.85 | CHRM4 (0.53) | DRD4DRD2CCR2 | |
| SCHEMBL2857724 | 0.82 | SIGMAR1 (0.53) | SIGMAR1 | |
| SCHEMBL2854556 | 0.76 | DRD4 (0.47) | DRD4DRD2SIGMAR1MCHR1 | |
| SCHEMBL10155707 | 0.74 | MCHR1 (0.61) | DRD4DRD2SIGMAR1MCHR1 | |
| SCHEMBL2855714 | 0.71 | EPHX1 (0.45) | — | |
| SCHEMBL2900711 | 0.71 | MAPT (0.40) | — | |
| SCHEMBL2852970 | 0.71 | DRD2 (0.51) | DRD4DRD2SIGMAR1CCR2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |