Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CCR2 | P41597 | 8/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857724 | 0.95 | SIGMAR1 (0.53) | SIGMAR1 | |
| SCHEMBL2859595 | 0.91 | CHRM4 (0.53) | DRD4DRD2CCR2BCHEACHE | |
| SCHEMBL2863246 | 0.87 | DRD4 (0.49) | DRD4DRD2CCR2SIGMAR1HDAC3 | |
| SCHEMBL2856452 | 0.87 | DRD4 (0.47) | DRD4DRD2CCR2SIGMAR1HDAC3 | |
| SCHEMBL2857980 | 0.86 | DRD4 (0.47) | DRD4DRD2CCR2SIGMAR1HDAC3 | |
| SCHEMBL2852970 | 0.84 | DRD2 (0.51) | DRD4DRD2CNR1CCR2SIGMAR1 | |
| SCHEMBL2853388 | 0.79 | CCR1 (0.48) | — | |
| SCHEMBL2854556 | 0.78 | DRD4 (0.47) | DRD4DRD2SIGMAR1BACE1 | |
| SCHEMBL2855547 | 0.77 | TAAR1 (0.54) | CNR1 | |
| SCHEMBL2856213 | 0.76 | CNR1 (0.47) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |