Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28597583 | 0.79 | PDE4B (0.45) | DRD2ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL2764499 | 0.78 | PNMT (0.50) | MEN1KMT2ANOS1KDM4E | |
| SCHEMBL28595960 | 0.78 | DHFR (0.50) | DRD2MEN1KMT2AGAADHFR | |
| SCHEMBL28917800 | 0.77 | CHRNB2 (0.51) | DRD2ALDH1A1TSHRKCNH2KDM4E | |
| SCHEMBL28587665 | 0.76 | KMT2A (0.54) | DRD2ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL28602029 | 0.75 | EED (0.37) | MEN1KMT2A | |
| SCHEMBL2483781 | 0.74 | PNMT (0.44) | DRD2ALDH1A1TSHRPOLB | |
| SCHEMBL28597675 | 0.74 | HTR7 (0.40) | DRD2ALDH1A1TSHRKDM4E | |
| SCHEMBL697563 | 0.72 | SIGMAR1 (0.50) | ALDH1A1MEN1KMT2ANOS1KDM4E | |
| SCHEMBL216386 | 0.72 | HDAC3 (0.39) | DRD2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166139-A | Pyrrolo [2,3-b ] pyridines as HPK1 inhibitors and uses thereof | 百济神州有限公司 | 2021-07-23 | — | — | CN | disclosed |