Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | ALDH1A3 | P47895 | 4/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29936108 | 0.78 | ALDH1A1 (0.45) | ALDH1A1ALDH1A3CYP2A6KCNJ1MEN1 | |
| SCHEMBL29935819 | 0.77 | ALDH1A1 (0.58) | ALDH1A1ALDH1A3CYP2A6TSHRMAPT | |
| SCHEMBL4082746 | 0.76 | ALDH1A1 (0.59) | ALDH1A1ALDH1A3CYP2A6TSHRMAPT | |
| SCHEMBL29935776 | 0.74 | KIF11 (0.49) | ALDH1A1ALDH1A3KCNJ1MEN1MAPT | |
| SCHEMBL3313274 | 0.73 | ALDH1A1 (0.55) | ALDH1A1TSHRMEN1GAAMAPT | |
| SCHEMBL21816384 | 0.71 | GAA (0.53) | ALDH1A1TSHRMEN1GAAMAPT | |
| SCHEMBL2511973 | 0.71 | KCNJ1 (0.53) | ALDH1A1CYP2A6KCNJ1KDM4ENPSR1 | |
| SCHEMBL29350085 | 0.71 | CYP2A6 (0.52) | ALDH1A1ALDH1A3CYP2A6TSHRHPGD | |
| SCHEMBL98097 | 0.71 | CYP2A6 (0.52) | ALDH1A1ALDH1A3CYP2A6TSHRHPGD | |
| SCHEMBL25487219 | 0.70 | ALDH1A1 (0.77) | ALDH1A1ALDH1A3MEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164458-B | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2024-09-13 | — | — | CN | claimed |
| CN-113164458-A | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2021-07-23 | — | — | CN | claimed |
| US-12577243-B2 | Monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2026-03-17 | — | — | US | disclosed |
| CN-113164458-B | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2024-09-13 | — | — | CN | disclosed |
| US-11820766-B2 | Monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-21 | — | — | US | disclosed |
| US-20230145249-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-05-11 | — | — | US | disclosed |
| US-20220332713-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2022-10-20 | — | — | US | disclosed |
| CN-113164458-A | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2021-07-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220332713-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | ALDH1A1 312/4885ALDH1A3 93/4885CYP2A6 747/4885 |
| US-12577243-B2 | Monoacylglycerol lipase modulators | MGLL, LPL, FAAH | ALDH1A1 587/4885ALDH1A3 132/4885CYP2A6 555/4885 |
| US-20230145249-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | ALDH1A1 312/4885ALDH1A3 93/4885CYP2A6 747/4885 |
| US-11820766-B2 | Monoacylglycerol lipase modulators | MGLL, LPL, PNLIP | ALDH1A1 312/4885ALDH1A3 93/4885CYP2A6 747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.