Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 4/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | EZH2 | Q15910 | 5/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | EZH1 | Q92800 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28596693 | 0.97 | EPHX2 (0.52) | EPHX2NR1H4PPARAPPARGEZH2 | |
| SCHEMBL28598243 | 0.84 | CCR5 (0.50) | EPHX2NR1H4EZH2 | |
| SCHEMBL28595709 | 0.84 | LSS (0.46) | EPHX2PPARAPPARGEZH2NAMPT | |
| SCHEMBL28601010 | 0.83 | EZH2 (0.45) | EZH2ROCK2ROCK1EZH1 | |
| SCHEMBL28919197 | 0.83 | RXRA (0.46) | EPHX2EZH2EZH1 | |
| SCHEMBL29473791 | 0.83 | RXRA (0.46) | EPHX2EZH2EZH1 | |
| SCHEMBL28597396 | 0.82 | CCR5 (0.48) | EPHX2PPARGEZH2EZH1 | |
| SCHEMBL28602816 | 0.82 | ALDH1A1 (0.49) | EZH2EZH1 | |
| SCHEMBL29473822 | 0.81 | SMN1; SMN2 (0.52) | NR1H4EZH2EZH1 | |
| SCHEMBL28613717 | 0.81 | SMN1; SMN2 (0.52) | NR1H4EZH2EZH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113045494-B | Pyridone derivative and application thereof in preparation of drugs for preventing and/or treating tuberculosis caused by mycobacterium tuberculosis | 四川大学华西医院 | 2022-04-26 | — | — | CN | disclosed |
| CN-113045494-A | Pyridone derivative and application thereof in preparation of drugs for preventing and/or treating tuberculosis caused by mycobacterium tuberculosis | 四川大学华西医院 | 2021-06-29 | — | — | CN | disclosed |