SCHEMBL31411802

SCHEMBL31411802

COS(=O)(=O)CC1CN(c2ccc3ccoc3c2)C1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCKAR P32238 1/20 0.34
CA2 P00918 2/20 0.33
PEPD P12955 1/20 0.33
XPNPEP1 Q9NQW7 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
GHSR Q92847 3/20 0.32
HTR3E A5X5Y0 1/20 0.32
HTR3B O95264 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA7 P36544 1/20 0.32
HTR3A P46098 1/20 0.32
HTR3D Q70Z44 1/20 0.32
HTR3C Q8WXA8 1/20 0.32
CA12 O43570 1/20 0.32
USP9X Q93008 1/20 0.31
FASN P49327 1/20 0.31
CHRM2 P08172 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31411540 0.76 CHRNA7 (0.36) CCKARSLC6A2SLC6A4SLC6A3HTR3E
SCHEMBL28731199 0.73 LMNA (0.46) HTR3EHTR3BHTR3AHTR3DHTR3C
SCHEMBL29059217 0.73 GHSR (0.38) CA2SLC6A2SLC6A4GHSR
SCHEMBL28593067 0.70 MEN1 (0.41)
SCHEMBL28601340 0.70 HRH3 (0.43)
SCHEMBL31411691 0.67 FFAR4 (0.39) CHRM3
SCHEMBL3789129 0.64 CHRM2 (0.42) CA2CA12CHRM2CHRM1CHRM3
SCHEMBL7814988 0.63 HTR3E (0.56) SLC6A4HTR3EHTR3BHTR3AHTR3D
SCHEMBL7814698 0.61 DRD2 (0.60) SLC6A2SLC6A4SLC6A3
SCHEMBL31411675 0.59 MAPT (0.42) CA2SLC6A2SLC6A4SLC6A3GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119330982-A Azetidine compound and medical application thereof 中国科学院上海药物研究所 2025-01-21 CN disclosed