Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 14/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733863 | 0.76 | MPO (0.56) | HTR1AMPOSLC6A4HTR2ATRPM8 | |
| SCHEMBL15902132 | 0.75 | GABRA1 (0.39) | — | |
| SCHEMBL28604357 | 0.74 | AR (0.31) | — | |
| SCHEMBL8140362 | 0.71 | MPO (0.55) | HTR1AMPOSLC6A4HTR2ATRPM8 | |
| SCHEMBL15901906 | 0.68 | HDAC1 (0.44) | HTR1AHTR1DHTR1B | |
| SCHEMBL22152521 | 0.67 | SLC6A4 (0.56) | HTR1AHTR7HTR6HTR1DHTR1B | |
| SCHEMBL25356197 | 0.65 | DUT (0.36) | — | |
| SCHEMBL30531080 | 0.65 | DUT (0.36) | — | |
| SCHEMBL8129433 | 0.64 | HTR2A (0.55) | HTR1AHTR7HTR6MPOSLC6A4 | |
| SCHEMBL5946187 | 0.64 | SLC6A4 (0.52) | HTR1AHTR7HTR6HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440370-B | Inhibitors of viral replication | 鲁汶天主教大学 | 2021-07-30 | — | — | CN | disclosed |