Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MECP2 | P51608 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | TNKS | O95271 | 3/20 | 0.46 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.45 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854574 | 0.90 | HSP90AA1 (0.51) | MAPTSMN1; SMN2LMNAHPGDKMT2A | |
| SCHEMBL2860254 | 0.84 | RAB9A (0.60) | MAPTTP53MAPK1MECP2SMN1; SMN2 | |
| SCHEMBL2852417 | 0.81 | MAPT (0.49) | MAPTTP53SMN1; SMN2LMNAKMT2A | |
| SCHEMBL2859099 | 0.78 | NPC1 (0.50) | MAPTSMN1; SMN2LMNATSHRKMT2A | |
| SCHEMBL2850131 | 0.78 | RAB9A (0.61) | MAPTTP53SMN1; SMN2LMNAHPGD | |
| SCHEMBL2856979 | 0.78 | RAB9A (0.46) | MAPTSMN1; SMN2RAB9ANPC1KDM4E | |
| SCHEMBL2850383 | 0.76 | KMT2A (0.47) | MAPTMAPK1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL2854503 | 0.76 | KDR (0.47) | MAPTSMN1; SMN2LMNAHPGDKMT2A | |
| SCHEMBL2853255 | 0.76 | HSP90AA1 (0.48) | MAPTSMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL2850858 | 0.76 | KDR (0.48) | MAPTSMN1; SMN2LMNAHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |