Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 14/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2859611 | 0.90 | CCR1 (0.53) | CCR1NPSR1MAPTHSP90AA1KDM4E | |
| SCHEMBL2852844 | 0.90 | LIPE (0.45) | CCR1NPSR1MAPTHSP90AA1KDM4E | |
| SCHEMBL2854177 | 0.84 | CCR1 (0.58) | CCR1NPSR1MAPTHSP90AA1KDM4E | |
| SCHEMBL2849956 | 0.83 | CCR1 (0.62) | CCR1NPSR1MAPTHSP90AA1 | |
| SCHEMBL2857735 | 0.82 | CCR1 (0.54) | CCR1NPSR1MAPTHSP90AA1KDM4E | |
| SCHEMBL2853814 | 0.80 | LIPE (0.43) | NPSR1MAPTKDM4ELIPE | |
| SCHEMBL2856483 | 0.79 | ALDH1A1 (0.45) | CCR1NPSR1MAPTHSP90AA1KDM4E | |
| SCHEMBL2848489 | 0.79 | POLB (0.44) | CCR1MAPTKDM4ELIPE | |
| SCHEMBL2854221 | 0.78 | MAPT (0.51) | CCR1NPSR1MAPTHSP90AA1KDM4E | |
| SCHEMBL2852819 | 0.77 | CCR1 (0.57) | CCR1NPSR1MAPTHSP90AA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |