Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 2/20 | 0.44 |
| ▸ | FLT4 | P35916 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856759 | 0.83 | ACLY (0.44) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL2860822 | 0.82 | MAPT (0.45) | MAPTMAPK14 | |
| SCHEMBL2859712 | 0.81 | CA1 (0.45) | MAPTSMN1; SMN2 | |
| SCHEMBL2850834 | 0.79 | NTRK1 (0.45) | MAPTSMN1; SMN2ALDH1A1TSHRMEN1 | |
| SCHEMBL2859374 | 0.78 | MAPT (0.52) | MAPTSMN1; SMN2 | |
| SCHEMBL2850809 | 0.78 | MAPT (0.43) | MAPTSMN1; SMN2ALDH1A1TSHRKMT2A | |
| SCHEMBL2850337 | 0.78 | MAPT (0.40) | MAPTGAASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL2854533 | 0.78 | MEN1 (0.46) | MAPTSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL2853465 | 0.77 | RAB9A (0.44) | MAPTGAASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL2852353 | 0.77 | RAB9A (0.44) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |