Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28602834 | 0.86 | SLC7A5 (0.38) | RAB9AKDM4EKMT2A | |
| SCHEMBL27872649 | 0.86 | PSMB11 (0.41) | POLBALDH1A1 | |
| SCHEMBL28766234 | 0.86 | PSMB11 (0.41) | POLBALDH1A1 | |
| SCHEMBL28611443 | 0.82 | POLB (0.43) | POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL28766231 | 0.76 | POLB (0.40) | POLBMAPTTDP1ALDH1A1 | |
| SCHEMBL28613880 | 0.72 | POLB (0.41) | HTTSMN1; SMN2KDM4EPOLBMEN1 | |
| SCHEMBL16078676 | 0.71 | LDHA (0.67) | LDHAHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL29153963 | 0.69 | LMNA (0.53) | RAB9AHTTSMN1; SMN2KDM4EPOLB | |
| SCHEMBL30873347 | 0.69 | LMNA (0.53) | RAB9AHTTSMN1; SMN2KDM4EPOLB | |
| SCHEMBL28595164 | 0.68 | RAB9A (0.63) | RAB9AHTTSMN1; SMN2MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008665-B | Compound with tumor proliferation inhibition function and preparation method and application thereof | 北京大学 | 2021-03-16 | — | — | CN | disclosed |