Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | FPR2 | P25090 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853389 | 0.90 | NPC1 (0.62) | FPR2KMT2AGLATAAR1NPC1 | |
| SCHEMBL2854531 | 0.90 | LMNA (0.52) | KMT2ANPC1RAB9AMEN1TP53 | |
| SCHEMBL2854313 | 0.89 | NPSR1 (0.54) | CNR1TAAR1TP53LMNA | |
| SCHEMBL2859872 | 0.89 | TAAR1 (0.54) | KMT2ATAAR1NPC1GAARAB9A | |
| SCHEMBL2857343 | 0.87 | P2RX7 (0.42) | CNR1KMT2AMEN1TP53ALDH1A1 | |
| SCHEMBL2858680 | 0.84 | NPC1 (0.45) | KMT2ATAAR1NPC1GAARAB9A | |
| SCHEMBL2856862 | 0.83 | NPC1 (0.53) | KMT2ATAAR1NPC1GAARAB9A | |
| SCHEMBL2857468 | 0.83 | MAPT (0.47) | NPC1RAB9ATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL2852384 | 0.82 | NPC1 (0.54) | CNR1KMT2ANPC1GAARAB9A | |
| SCHEMBL2850323 | 0.82 | MAPT (0.47) | KMT2AGLATAAR1NPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |