Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | CCR1 | P32246 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | VNN1 | O95497 | 1/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2861643 | 0.90 | CNR1 (0.50) | LMNARXFP1ABCB1TP53SMN1; SMN2 | |
| SCHEMBL2854802 | 0.90 | LMNA (0.48) | LMNACCR1MAPTTP53ALDH1A1 | |
| SCHEMBL2860234 | 0.89 | HPGD (0.54) | RXFP1MAPTTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL2857180 | 0.88 | NPSR1 (0.53) | RXFP1CCR1MAPTTP53POLB | |
| SCHEMBL2852334 | 0.88 | HPGD (0.55) | LMNACCR1MAPTTP53SMN1; SMN2 | |
| SCHEMBL2848661 | 0.86 | ABCB1 (0.48) | LMNARXFP1ABCB1CCR1MAPT | |
| SCHEMBL2852384 | 0.84 | NPC1 (0.54) | LMNAMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL2852238 | 0.84 | GAA (0.55) | TP53SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL2853335 | 0.84 | TP53 (0.48) | MAPTTP53SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL2852082 | 0.83 | CCR1 (0.72) | LMNARXFP1ABCB1CCR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |