Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852350 | 0.92 | NPC1 (0.53) | TAAR1TP53NPC1RAB9AGAA | |
| SCHEMBL2854313 | 0.90 | NPSR1 (0.54) | TAAR1TP53LMNA | |
| SCHEMBL2852334 | 0.89 | HPGD (0.55) | TP53SMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL2861643 | 0.89 | CNR1 (0.50) | TAAR1TP53SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL2856513 | 0.87 | TAAR1 (0.51) | TAAR1TP53SMN1; SMN2KMT2ARAB9A | |
| SCHEMBL2854704 | 0.86 | P2RX7 (0.48) | TP53SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL2856602 | 0.85 | RIPK1 (0.46) | TP53KMT2AMEN1HPGD | |
| SCHEMBL2854887 | 0.85 | HPGD (0.49) | SMN1; SMN2NPC1RAB9AHPGDNR3C1 | |
| SCHEMBL2859861 | 0.85 | TAAR1 (0.51) | TAAR1TP53SMN1; SMN2KMT2ALMNA | |
| SCHEMBL2853389 | 0.84 | NPC1 (0.62) | TAAR1TP53SMN1; SMN2KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |