SCHEMBL28619339

SCHEMBL28619339

O=c1nc(NNO)cc[nH]1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32
ALDH1A1 P00352 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N4-Hydroxycytosine SCHEMBL48396 0.83
SCHEMBL28034702 0.81 ALDH1A1 (0.51) ALDH1A1
SCHEMBL8899069 0.77 L3MBTL1 (0.35) ADORA1ALDH1A1
SCHEMBL27926563 0.76 FEN1 (0.32)
SCHEMBL5985571 0.74
SCHEMBL3133642 0.74
SCHEMBL11894063 0.74
SCHEMBL8944768 0.74
SCHEMBL7876670 0.74
SCHEMBL19692379 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113278040-B Preparation method of 5' -isobutyryl-N4-hydroxycytidine 苏州立新制药有限公司 2022-07-05 CN claimed
CN-113307833-B Preparation method of N4-hydroxycytidine 苏州立新制药有限公司 2022-07-05 CN claimed
CN-113307833-A Preparation method of N4-hydroxycytidine 苏州立新制药有限公司 2021-08-27 CN claimed
CN-113278040-A Preparation method of 5' -isobutyryl-N4-hydroxycytidine 苏州立新制药有限公司 2021-08-20 CN claimed