Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | GAA | P10253 | 8/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21187 | 0.81 | KDM4E (0.47) | CYP1A2KDM4EMAPTLMNAROCK2 | |
| SCHEMBL8899069 | 0.81 | L3MBTL1 (0.35) | ALDH1A1GAACYP3A4TSHRCYP1A2 | |
| SCHEMBL1827089 | 0.80 | KDM4E (0.46) | CYP1A2KDM4EMAPTLMNAROCK2 | |
| Methane SCHEMBL27916786 | 0.80 | KDM4E (0.46) | CYP1A2KDM4EMAPTLMNAROCK2 | |
| SCHEMBL3571371 | 0.77 | DYRK1A (0.35) | — | |
| SCHEMBL5065536 | 0.74 | TDO2 (0.43) | ALDH1A1CYP3A4CYP1A2ELANENPSR1 | |
| SCHEMBL13425959 | 0.74 | ADORA2A (0.31) | ELANEROCK2PIK3C3 | |
| Cytosine SCHEMBL6839375 | 0.73 | KDM4E (0.41) | KDM4EMAPTLMNAROCK2PIK3C3 | |
| N4-Hydroxycytosine SCHEMBL48396 | 0.72 | — | — | |
| SCHEMBL27952254 | 0.72 | NCF1 (0.39) | ALDH1A1CYP3A4CYP1A2ELANEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104926806-B | Method for synthesizing lamivudine intermediate | 上海创诺制药有限公司 | 2020-03-24 | — | — | CN | disclosed |
| CN-104926806-B | Method for synthesizing lamivudine intermediate | 上海创诺制药有限公司 | 2020-03-24 | — | — | CN | disclosed |
| CN-104926806-A | Synthetic method of lamivudine intermediate | SHANGHAI ACEBRIGHT PHARMACEUTICAL CO LTD | 2015-09-23 | — | — | CN | disclosed |