Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 14/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854340 | 0.90 | CCR1 (0.53) | CCR1NPSR1KDM4EMAPTHSP90AA1 | |
| SCHEMBL2857365 | 0.87 | CCR1 (0.49) | CCR1NPSR1KDM4EMAPT | |
| SCHEMBL2853261 | 0.86 | SPR (0.48) | CCR1NPSR1KDM4EMAPT | |
| SCHEMBL2857468 | 0.85 | MAPT (0.47) | CCR1NPSR1KDM4EMAPT | |
| SCHEMBL2854225 | 0.83 | CCR1 (0.60) | CCR1NPSR1KDM4EMAPTHSP90AA1 | |
| SCHEMBL2862820 | 0.82 | P2RX7 (0.45) | CCR1NPSR1KDM4EMAPTCNR1 | |
| SCHEMBL2863198 | 0.82 | CCR1 (0.50) | CCR1NPSR1KDM4EMAPTROCK2 | |
| SCHEMBL2857735 | 0.82 | CCR1 (0.54) | CCR1NPSR1KDM4EMAPTHSP90AA1 | |
| SCHEMBL2854313 | 0.81 | NPSR1 (0.54) | CCR1NPSR1MAPTCNR1 | |
| SCHEMBL2860847 | 0.81 | CCR1 (0.55) | CCR1NPSR1KDM4EMAPTHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |