Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMO | Q99835 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852556 | 0.88 | TDP1 (0.44) | SPRTDP1CCR1MAPTTP53 | |
| SCHEMBL2857365 | 0.88 | CCR1 (0.49) | CCR1MAPTTP53NPC1RAB9A | |
| SCHEMBL2862272 | 0.86 | CCR1 (0.61) | CCR1MAPTKDM4ENPSR1 | |
| SCHEMBL2857468 | 0.86 | MAPT (0.47) | SPRSMOCCR1MAPTTP53 | |
| SCHEMBL2853389 | 0.84 | NPC1 (0.62) | MAPTTP53NPC1RAB9AALDH1A1 | |
| SCHEMBL2851589 | 0.83 | MTNR1A (0.48) | MAPTTP53ALDH1A1 | |
| SCHEMBL2854313 | 0.82 | NPSR1 (0.54) | SPRTDP1CCR1MAPTTP53 | |
| SCHEMBL2854586 | 0.81 | ALDH1A1 (0.47) | SPRMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL2854802 | 0.81 | LMNA (0.48) | CCR1MAPTTP53ALDH1A1POLB | |
| SCHEMBL2863131 | 0.80 | CNR1 (0.50) | SPRCCR1MAPTTAAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |