Butane

Butane

SCHEMBL2862770

CCCC.O=C(O)CCC(=O)Oc1ccc(Cl)cc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.53
MAPT P10636 2/20 0.53
LMNA P02545 2/20 0.53
ALDH1A1 P00352 1/20 0.53
HTT P42858 1/20 0.53
HSD17B10 Q99714 1/20 0.53
BCL9 O00512 1/20 0.46
CTNNB1 P35222 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ELANE P08246 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2D6 P10635 2/20 0.41
CYP2C19 P33261 2/20 0.41
CYP2C9 P11712 1/20 0.41
PPARA Q07869 2/20 0.41
MEN1 O00255 1/20 0.41
CYP3A4 P08684 1/20 0.41
ESR1 P03372 1/20 0.41
RECQL P46063 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19690545 0.93 KMT2A (0.55) KMT2AMAPTLMNAALDH1A1HTT
Succinic Acid Diethyl Ester SCHEMBL28562314 0.89 KMT2A (0.49) KMT2AMAPTLMNAALDH1A1HTT
SCHEMBL28782938 0.88 KMT2A (0.50) KMT2AMAPTLMNAALDH1A1HTT
SCHEMBL5468900 0.86 BCL9 (0.60) KMT2AMAPTLMNAALDH1A1HTT
SCHEMBL643983 0.86 KMT2A (0.63) KMT2AMAPTLMNAALDH1A1HTT
Butane SCHEMBL2851843 0.85 KMT2A (0.59) KMT2AMAPTLMNAALDH1A1HTT
Butane SCHEMBL1041531 0.85 KMT2A (0.49) KMT2AMAPTLMNAALDH1A1HTT
Butane SCHEMBL2853445 0.84 KMT2A (0.53) KMT2AMAPTLMNAALDH1A1HTT
SCHEMBL6344321 0.83 KMT2A (0.55) KMT2AMAPTLMNAALDH1A1HTT
SCHEMBL27514586 0.81 KMT2A (0.55) KMT2AMAPTLMNAALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116199995-A High-fluidity polypropylene resin composition and molded article made from the same 韩华道达尔能源有限公司 2023-06-02 CN claimed
CN-116997578-A Prepolymerized catalyst component for olefin polymerization 巴塞尔聚烯烃意大利有限公司 2023-11-03 CN disclosed
CN-116199995-A High-fluidity polypropylene resin composition and molded article made from the same 韩华道达尔能源有限公司 2023-06-02 CN disclosed
CN-112204055-B Polypropylene composition and molded article 巴塞尔聚烯烃意大利有限公司 2022-01-18 CN disclosed
US-11136421-B2 Solid catalyst component for use in olefin polymerisation, catalyst, and application thereof BEIJING LIHE TECHNOLOGY LTD (CN) 2021-10-05 US disclosed
CN-107915794-B Catalyst component for olefin polymerization and application thereof, catalyst for olefin polymerization and application thereof, and olefin polymerization method 中国石油化工股份有限公司 2021-03-16 CN disclosed
US-20200071430-A1 SOLID CATALYST COMPONENT FOR USE IN OLEFIN POLYMERISATION, CATALYST, AND APPLICATION THEREOF BEIJING LIHE TECH LTD (CN) 2020-03-05 US disclosed
US-20190169328-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF RENQIU LIHE TECH LTD (CN) 2019-06-06 US disclosed
US-20170355792-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF RENQIU LIHE TECH LTD (CN) 2017-12-14 US disclosed
US-8822366-B2 Solid titanium catalyst component, catalyst for olefin polymerization and process for polymerizing olefin MITSUI CHEMICALS, INC. (JP) 2014-09-02 US disclosed
EP-2206731-B1 SOLID TITANIUM CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, AND OLEFIN POLYMERIZATION METHOD MITSUI CHEMICALS INC (JP) 2013-08-28 EP disclosed
US-20100227991-A1 SOLID TITANIUM CATALYST COMPONENT, CATALIST FOR OLEFIN POLYMERIZATION AND PROCESS FOR POLYMERIZING OLEFIN MITSUI CHEMICALS, INC. (JP) 2010-09-09 US disclosed
EP-2206731-A1 SOLID TITANIUM CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, AND OLEFIN POLYMERIZATION METHOD Mitsui Chemicals, Inc. (JP) 2010-07-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190169328-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF COG2, GTF2I, POF1B KMT2A 2142/4885MAPT 2703/4885LMNA 2302/4885
US-20170355792-A1 OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF COG2, COG7, COG4 KMT2A 2597/4885MAPT 3639/4885LMNA 3701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.