Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 3/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28252209 | 0.77 | L3MBTL1 (0.38) | OPRD1PRCPL3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL28617084 | 0.75 | BRD4 (0.37) | ALDH1A1HPGDKMT2A | |
| SCHEMBL28388144 | 0.72 | PTAFR (0.31) | — | |
| SCHEMBL8064992 | 0.69 | L3MBTL1 (0.37) | OPRD1L3MBTL1LMNAALDH1A1HSD17B10 | |
| SCHEMBL28623484 | 0.65 | HPGD (0.40) | LMNAALDH1A1HPGDKDM4E | |
| SCHEMBL6684665 | 0.64 | PRCP (0.45) | OPRD1PRCPALDH1A1HSD17B10KDM4E | |
| SCHEMBL9446993 | 0.61 | BRD4 (0.42) | LMNAALDH1A1HPGD | |
| SCHEMBL22700996 | 0.61 | CHRM2 (0.39) | OPRD1PRCPLMNAALDH1A1HSD17B10 | |
| SCHEMBL7691670 | 0.61 | ALDH1A1 (0.37) | OPRD1PRCPL3MBTL1LMNAALDH1A1 | |
| SCHEMBL28617339 | 0.60 | PTGS2 (0.37) | L3MBTL1LMNAALDH1A1HSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108822037-B | Method for efficiently synthesizing imidazoline derivative with high atom economy | 复旦大学 | 2021-08-20 | — | — | CN | claimed |
| CN-108822037-B | Method for efficiently synthesizing imidazoline derivative with high atom economy | 复旦大学 | 2021-08-20 | — | — | CN | disclosed |