Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28543844 | 0.75 | TDP2 (0.35) | TDP2NSD2HSP90AA1PAX8KDM4E | |
| Hydrochloric Acid SCHEMBL27500044 | 0.74 | TDP2 (0.32) | TDP2NSD2HSP90AA1PAX8 | |
| SCHEMBL27744758 | 0.71 | TDP2 (0.32) | TDP2NSD2HSP90AA1PAX8 | |
| Hydrochloric Acid SCHEMBL5608870 | 0.66 | CEL (0.30) | — | |
| Hydrochloric Acid SCHEMBL7821332 | 0.64 | TDP2 (0.31) | TDP2NSD2HSP90AA1PAX8 | |
| SCHEMBL28011736 | 0.64 | TDP2 (0.33) | TDP2NSD2HSP90AA1PAX8KDM4E | |
| SCHEMBL7634413 | 0.64 | TDP2 (0.33) | TDP2NSD2HSP90AA1PAX8KDM4E | |
| Hydrochloric Acid SCHEMBL4079003 | 0.63 | GPR3 (0.35) | — | |
| Hydrochloric Acid SCHEMBL8847734 | 0.61 | — | — | |
| Hydrochloric Acid SCHEMBL146139 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166293-A | Process for preparing catalyst for polymerizing olefins | 韩华思路信株式会社 | 2021-07-23 | — | — | CN | disclosed |