Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | FPR1 | P21462 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.38 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.38 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.38 |
| ▸ | MAP3K4 | Q9Y6R4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856997 | 0.75 | ALDH1A1 (0.57) | ALDH1A1MAPK1MAPTGAAMAPK14 | |
| SCHEMBL5325459 | 0.74 | ALDH1A1 (0.53) | ALDH1A1MAPK1MAPTGAAMAPK14 | |
| SCHEMBL2925505 | 0.74 | CNR1 (0.47) | ALDH1A1MAPTGAAMAPK14LMNA | |
| SCHEMBL2850151 | 0.73 | RAB9A (0.48) | ALDH1A1MAPK1RAB9A | |
| SCHEMBL2850487 | 0.73 | HTT (0.48) | ALDH1A1MAPK1 | |
| SCHEMBL2854713 | 0.72 | NTRK1 (0.49) | ALDH1A1MAPK1MAPTGAAMAPK14 | |
| SCHEMBL2852492 | 0.72 | ALDH1A1 (0.53) | ALDH1A1MAPK1MAPTGAAMAPK14 | |
| SCHEMBL2858605 | 0.71 | MAPT (0.53) | ALDH1A1MAPK1MAPTGAAMAPK14 | |
| SCHEMBL2856275 | 0.71 | ALDH1A1 (0.52) | ALDH1A1MAPK1MAPTGAARAB9A | |
| SCHEMBL2860824 | 0.71 | LMNA (0.57) | ALDH1A1MAPK1MAPTGAAMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |