Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30632156 | 0.88 | MGLL (0.56) | PLA2G7MGLLABHD6FAAH | |
| SCHEMBL28614777 | 0.88 | MGLL (0.56) | PLA2G7MGLLABHD6FAAH | |
| SCHEMBL28447724 | 0.86 | MGLL (0.68) | PLA2G7MGLLABHD6GPR119FAAH | |
| SCHEMBL30141417 | 0.86 | MGLL (0.68) | PLA2G7MGLLABHD6GPR119FAAH | |
| SCHEMBL5335100 | 0.84 | PLA2G7 (0.61) | PLA2G7MGLLABHD6GPR119FAAH | |
| SCHEMBL5335298 | 0.83 | MGLL (0.60) | PLA2G7MGLLABHD6GPR119FAAH | |
| SCHEMBL3843148 | 0.82 | NAMPT (0.66) | GPR119NAMPTMEN1KMT2ATP53 | |
| SCHEMBL6132848 | 0.82 | GPR119 (0.69) | GPR119NAMPTTP53MAPT | |
| SCHEMBL28613846 | 0.81 | OPRM1 (0.55) | PLA2G7MGLLABHD6MEN1KMT2A | |
| SCHEMBL5336442 | 0.81 | MGLL (0.53) | PLA2G7MGLLABHD6GPR119NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292485-B | Benzyl piperazine urea TRPV1 antagonizing and MOR agonizing double-target medicine and its prepn and application | 河南大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-113292485-A | Benzylpiperazine urea TRPV1 antagonistic and MOR agonistic double-target-point medicine, preparation method and application | 河南大学 | 2021-08-24 | — | — | CN | disclosed |