Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | GPR183 | P32249 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.43 |
| ▸ | ITGAL | P20701 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28615980 | 0.91 | POLB (0.56) | ALDH1A1POLBSMN1; SMN2MAOBGAA | |
| SCHEMBL28634881 | 0.89 | GAA (0.48) | POLBSMN1; SMN2GAAMAPTLMNA | |
| SCHEMBL28620970 | 0.88 | MAPT (0.49) | ALDH1A1POLBSMN1; SMN2GAAMAPT | |
| SCHEMBL28616300 | 0.87 | GPR183 (0.51) | ALDH1A1SMN1; SMN2LMNAGPR183HPGD | |
| SCHEMBL28620396 | 0.87 | LMNA (0.48) | MAPTLMNAGPR183HPGDHTT | |
| SCHEMBL28620401 | 0.87 | GPR183 (0.55) | ALDH1A1MAPTLMNAGPR183 | |
| SCHEMBL28617479 | 0.85 | STAT3 (0.52) | ALDH1A1SMN1; SMN2GAAMAPTLMNA | |
| SCHEMBL28620945 | 0.84 | GPR183 (0.50) | SMN1; SMN2GAAMAPTGPR183L3MBTL1 | |
| SCHEMBL28615982 | 0.83 | MAPT (0.52) | ALDH1A1SMN1; SMN2GAAMAPTLMNA | |
| SCHEMBL28665638 | 0.82 | MAPT (0.48) | POLBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440440-B | Naphthalene ring-containing 1,2, 4-oxadiazole-cinnamoyl piperazine compound and preparation method and application thereof | 贵州医科大学 | 2021-07-13 | — | — | CN | disclosed |