Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ME2 | P23368 | 1/20 | 0.47 |
| ▸ | ME1 | P48163 | 1/20 | 0.47 |
| ▸ | ME3 | Q16798 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CCNC | P24863 | 2/20 | 0.45 |
| ▸ | CDK8 | P49336 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GPR183 | P32249 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28620396 | 0.92 | LMNA (0.48) | ARCCNCCDK8MAPTLMNA | |
| SCHEMBL28620401 | 0.92 | GPR183 (0.55) | KMT2ARAB9AMAPTLMNANPC1 | |
| SCHEMBL28616300 | 0.92 | GPR183 (0.51) | LMNAGPR183SMN1; SMN2TP53 | |
| SCHEMBL28617767 | 0.91 | L3MBTL1 (0.55) | GAAL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL28617649 | 0.91 | LMNA (0.48) | GAAL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL28620716 | 0.91 | MAPT (0.45) | GAAL3MBTL1ARCCNCCDK8 | |
| SCHEMBL28617479 | 0.90 | STAT3 (0.52) | GAAL3MBTL1MEN1KMT2ACCNC | |
| SCHEMBL28633212 | 0.89 | ALDH1A1 (0.53) | GAAL3MBTL1POLBMAPTLMNA | |
| SCHEMBL28620945 | 0.89 | GPR183 (0.50) | GAAL3MBTL1RAB9ACCNCCDK8 | |
| SCHEMBL28627425 | 0.88 | LMNA (0.51) | GAAL3MBTL1POLBCCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440440-B | Naphthalene ring-containing 1,2, 4-oxadiazole-cinnamoyl piperazine compound and preparation method and application thereof | 贵州医科大学 | 2021-07-13 | — | — | CN | disclosed |