Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.55 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.55 |
| ▸ | ITGAL | P20701 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28633212 | 0.91 | ALDH1A1 (0.53) | POLBGAAALDH1A1L3MBTL1ITGB2 | |
| SCHEMBL28634881 | 0.87 | GAA (0.48) | POLBGAAL3MBTL1MAPTLMNA | |
| SCHEMBL28617649 | 0.86 | LMNA (0.48) | POLBGAAALDH1A1L3MBTL1MAPT | |
| SCHEMBL28620716 | 0.86 | MAPT (0.45) | GAAALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL28617767 | 0.86 | L3MBTL1 (0.55) | POLBGAAALDH1A1L3MBTL1MAPT | |
| SCHEMBL28620970 | 0.86 | MAPT (0.49) | POLBGAAALDH1A1L3MBTL1ITGB2 | |
| SCHEMBL28627425 | 0.84 | LMNA (0.51) | POLBGAAALDH1A1L3MBTL1MAPT | |
| SCHEMBL28620401 | 0.82 | GPR183 (0.55) | ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL28620396 | 0.82 | LMNA (0.48) | MAPTLMNAHTTHPGD | |
| SCHEMBL28616300 | 0.82 | GPR183 (0.51) | ALDH1A1LMNASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440440-B | Naphthalene ring-containing 1,2, 4-oxadiazole-cinnamoyl piperazine compound and preparation method and application thereof | 贵州医科大学 | 2021-07-13 | — | — | CN | disclosed |