Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 10/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28634881 | 0.92 | GAA (0.48) | GPR183LMNATP53KMT2AMAPT | |
| SCHEMBL28617767 | 0.91 | L3MBTL1 (0.55) | GPR183ALDH1A1LMNATP53KMT2A | |
| SCHEMBL28616300 | 0.91 | GPR183 (0.51) | GPR183ALDH1A1LMNATP53KCNH2 | |
| SCHEMBL28620396 | 0.91 | LMNA (0.48) | GPR183LMNATP53KCNH2HDAC1 | |
| SCHEMBL28617479 | 0.90 | STAT3 (0.52) | GPR183ALDH1A1LMNATP53KMT2A | |
| SCHEMBL28633212 | 0.87 | ALDH1A1 (0.53) | GPR183ALDH1A1LMNAMAPT | |
| SCHEMBL28620945 | 0.87 | GPR183 (0.50) | GPR183MAPTNPC1RAB9A | |
| SCHEMBL28617647 | 0.87 | CCNC (0.48) | GPR183ALDH1A1LMNATP53KMT2A | |
| SCHEMBL28615982 | 0.87 | MAPT (0.52) | GPR183ALDH1A1LMNATP53KMT2A | |
| SCHEMBL28627421 | 0.85 | L3MBTL1 (0.54) | ALDH1A1LMNAKMT2AMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440440-B | Naphthalene ring-containing 1,2, 4-oxadiazole-cinnamoyl piperazine compound and preparation method and application thereof | 贵州医科大学 | 2021-07-13 | — | — | CN | disclosed |