Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.52 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL6448903 | 1.00 | HTR6 (0.52) | HTR6DUSP3PTPN5PTPN11CA2 | |
| SCHEMBL597671 | 0.97 | HTR6 (0.55) | HTR6DUSP3PTPN5PTPN11CA2 | |
| SCHEMBL6740023 | 0.97 | HTR6 (0.55) | HTR6DUSP3PTPN5PTPN11CA2 | |
| SCHEMBL3409456 | 0.97 | HTR6 (0.55) | HTR6DUSP3PTPN5PTPN11CA2 | |
| SCHEMBL1981609 | 0.97 | HTR6 (0.55) | HTR6DUSP3PTPN5PTPN11CA2 | |
| SCHEMBL28929 | 0.97 | HTR6 (0.55) | HTR6DUSP3PTPN5PTPN11CA2 | |
| SCHEMBL11761400 | 0.97 | HTR6 (0.55) | HTR6DUSP3PTPN5PTPN11CA2 | |
| SCHEMBL28477667 | 0.97 | HTR6 (0.55) | HTR6DUSP3PTPN5PTPN11CA2 | |
| Water SCHEMBL8617713 | 0.94 | HTR6 (0.52) | HTR6DUSP3PTPN5PTPN11CA2 | |
| Water SCHEMBL22581636 | 0.94 | ALDH1A1 (0.55) | HTR6DUSP3PTPN5PTPN11CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112023726-B | Low-energy-consumption high-flux reverse osmosis membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2022-07-12 | — | — | CN | claimed |
| CN-109912470-B | Synthetic method of 3- (benzenesulfonyl) propionic acid | 苏州华道生物药业股份有限公司 | 2021-01-05 | — | — | CN | claimed |
| CN-119855576-A | Dental product with reduced extrusion force | 舒万诺知识产权公司 | 2025-04-18 | — | — | CN | disclosed |
| CN-112055579-B | One-component dental adhesive composition for fixing dental composite materials | 3M创新有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-113164444-A | DOCK1 inhibiting compounds and uses thereof | 国立大学法人九州大学 | 2021-07-23 | — | — | CN | disclosed |
| CN-109912470-B | Synthetic method of 3- (benzenesulfonyl) propionic acid | 苏州华道生物药业股份有限公司 | 2021-01-05 | — | — | CN | disclosed |
| CN-112055579-A | One-component dental adhesive composition for fixing dental composite material | 3M创新有限公司 | 2020-12-08 | — | — | CN | disclosed |
| CN-110678160-A | Dental adhesive composition, its preparation and use | 3M创新有限公司 | 2020-01-10 | — | — | CN | disclosed |
| US-20160040067-A1 | LIQUID CRYSTAL COMPOUND HAVING BUTENE-BONDING GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |
| US-8580146-B2 | Liquid crystal compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-11-12 | — | — | US | disclosed |
| EP-2206695-B1 | TETRA- OR PENTA-CYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC CORP (JP) | 2013-09-18 | — | — | EP | disclosed |
| CN-1854135-B | Heteronuclear compound with dicyandiamide connection and its medicinal use | LI WEIZHANG | 2013-06-12 | — | — | CN | disclosed |
| US-20120193577-A1 | LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2012-08-02 | — | — | US | disclosed |
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |
| US-20100309402-A1 | FOUR- OR FIVE-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 2010-12-09 | — | — | US | disclosed |
| EP-2206695-A1 | TETRA- OR PENTA-CYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | Chisso Corporation (JP) | 2010-07-14 | — | — | EP | disclosed |
| CN-1854135-A | Heteronuclear compound with dicyandiamide connection and its medicinal use | LI WEIZHANG (CN) | 2006-11-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100309402-A1 | FOUR- OR FIVE-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | KIF23, HCN3, FZD7 | HTR6 2022/4885DUSP3 708/4885PTPN5 902/4885 |
| US-20160040067-A1 | LIQUID CRYSTAL COMPOUND HAVING BUTENE-BONDING GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | CXCR1, PIEZO1, L1CAM | HTR6 3350/4885DUSP3 4800/4885PTPN5 3966/4885 |
| US-20120193577-A1 | LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | KIF23, MARK3, CCND3 | HTR6 2870/4885DUSP3 493/4885PTPN5 2131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.