Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 15/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28311125 | 0.85 | ALDH1A1 (0.43) | LMNA | |
| SCHEMBL6204947 | 0.82 | LMNA (0.37) | LMNA | |
| SCHEMBL28645585 | 0.81 | PTPN1 (0.40) | BRD4LMNA | |
| SCHEMBL5310644 | 0.79 | TSHR (0.44) | LMNA | |
| SCHEMBL27511647 | 0.79 | HTT (0.44) | LMNA | |
| SCHEMBL28488096 | 0.79 | TSHR (0.39) | LMNA | |
| SCHEMBL6421674 | 0.78 | NCF1 (0.36) | LMNA | |
| SCHEMBL27828724 | 0.78 | CA12 (0.40) | LMNA | |
| Water SCHEMBL28355074 | 0.77 | HTT (0.42) | LMNA | |
| SCHEMBL28305681 | 0.77 | MAPT (0.43) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113490670-B | Nitrogen-containing polycyclic condensed ring compound, pharmaceutical composition, preparation method and application thereof | 北京志健金瑞生物医药科技有限公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-113490670-A | Nitrogen-containing polycyclic fused ring compound, and pharmaceutical composition, preparation method and application thereof | 北京志健金瑞生物医药科技有限公司 | 2021-10-08 | — | — | CN | disclosed |