Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 10/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.30 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | CCR8 | P51685 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28640739 | 0.77 | MAPT (0.44) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL28925090 | 0.76 | NPC1 (0.32) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28651923 | 0.72 | RIPK1 (0.35) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL28631825 | 0.71 | LMNA (0.41) | ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL28993162 | 0.71 | NPC1 (0.36) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19002591 | 0.70 | ALDH1A1 (0.47) | CRHR1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28640774 | 0.69 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL7983100 | 0.69 | NR1H3 (0.39) | CRHR1ALDH1A1SMN1; SMN2DRD1KCNH2 | |
| SCHEMBL28925133 | 0.68 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9792783 | 0.68 | UHRF1 (0.54) | CRHR1DRD1UHRF1CCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113493419-A | EGFR tyrosine kinase inhibitor and application thereof | 南京药石科技股份有限公司 | 2021-10-12 | — | — | CN | disclosed |