Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | LYN | P07948 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28925133 | 0.81 | ALDH1A1 (0.42) | ALDH1A1LMNASMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL28993170 | 0.77 | ACHE (0.46) | ALDH1A1LMNAGAAMAPTL3MBTL1 | |
| SCHEMBL28631825 | 0.76 | LMNA (0.41) | ALDH1A1LMNASMN1; SMN2TDP1HTT | |
| SCHEMBL28651923 | 0.75 | RIPK1 (0.35) | ALDH1A1SMN1; SMN2GAAL3MBTL1KMT2A | |
| SCHEMBL28640739 | 0.74 | MAPT (0.44) | ALDH1A1LMNASMN1; SMN2GAAMAPT | |
| SCHEMBL16188033 | 0.73 | ALDH1A1 (0.50) | ALDH1A1LMNASMN1; SMN2GAAPTGS1 | |
| SCHEMBL8234336 | 0.70 | AR (0.49) | ALDH1A1LMNASMN1; SMN2GAAPTGS1 | |
| SCHEMBL28641325 | 0.69 | L3MBTL1 (0.43) | ALDH1A1SMN1; SMN2GAAMAPTL3MBTL1 | |
| SCHEMBL28645581 | 0.69 | CASP1 (0.43) | ALDH1A1LMNASMN1; SMN2GAAPTGS1 | |
| SCHEMBL28633472 | 0.69 | CETP (0.35) | ALDH1A1SMN1; SMN2L3MBTL1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113493419-A | EGFR tyrosine kinase inhibitor and application thereof | 南京药石科技股份有限公司 | 2021-10-12 | — | — | CN | disclosed |