Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.70 |
| ▸ | FABP3 | P05413 | 7/20 | 0.61 |
| ▸ | TERT | O14746 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8678511 | 0.96 | CA2 (0.76) | CA2FABP3MAPTBLMNPSR1 | |
| SCHEMBL11273289 | 0.96 | CA2 (0.76) | CA2FABP3MAPTBLMNPSR1 | |
| SCHEMBL9132842 | 0.96 | CA2 (0.76) | CA2FABP3MAPTBLMNPSR1 | |
| SCHEMBL11273293 | 0.96 | CA2 (0.76) | CA2FABP3MAPTBLMNPSR1 | |
| SCHEMBL11273298 | 0.96 | CA2 (0.76) | CA2FABP3MAPTBLMNPSR1 | |
| SCHEMBL28626709 | 0.96 | CA2 (0.76) | CA2FABP3MAPTBLMNPSR1 | |
| SCHEMBL28362946 | 0.96 | CA2 (0.76) | CA2FABP3MAPTBLMNPSR1 | |
| Sulfuric Acid SCHEMBL325122 | 0.90 | CA2 (0.67) | CA2FABP3MAPTBLMNPSR1 | |
| Sulfuric Acid SCHEMBL2231589 | 0.89 | CA2 (0.70) | CA2FABP3MAPTBLMNPSR1 | |
| SCHEMBL11156251 | 0.89 | CA2 (0.65) | CA2FABP3NPSR1FAAHCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111265432-B | Refreshing skin-moistening shower gel and preparation method thereof | 广州玥颜化妆品有限公司 | 2023-01-17 | — | — | CN | disclosed |
| CN-109563439-B | Cleaning composition | 因诺斯佩克活性化学物有限责任公司 | 2021-10-12 | — | — | CN | disclosed |