Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.76 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.52 |
| ▸ | FABP3 | P05413 | 7/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28362946 | 1.00 | CA2 (0.76) | CA2FABP3NPSR1CYP3A4TSHR | |
| SCHEMBL11273289 | 1.00 | CA2 (0.76) | CA2FABP3NPSR1CYP3A4TSHR | |
| SCHEMBL8678511 | 1.00 | CA2 (0.76) | CA2FABP3NPSR1CYP3A4TSHR | |
| SCHEMBL11273293 | 1.00 | CA2 (0.76) | CA2FABP3NPSR1CYP3A4TSHR | |
| SCHEMBL9132842 | 1.00 | CA2 (0.76) | CA2FABP3NPSR1CYP3A4TSHR | |
| SCHEMBL11273298 | 1.00 | CA2 (0.76) | CA2FABP3NPSR1CYP3A4TSHR | |
| Potassium Ion SCHEMBL28636809 | 0.96 | CA2 (0.70) | CA2FABP3NPSR1CYP3A4TSHR | |
| Sulfuric Acid SCHEMBL325122 | 0.94 | CA2 (0.67) | CA2FABP3NPSR1CYP3A4TSHR | |
| SCHEMBL11156251 | 0.92 | CA2 (0.65) | CA2FABP3NPSR1CYP3A4TSHR | |
| Sulfuric Acid SCHEMBL327638 | 0.92 | CA2 (0.70) | CA2FABP3NPSR1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119614142-A | Silicone sealant with modified heavy calcium partially substituted for nano calcium carbonate and preparation method thereof | 湖北兴发化工集团股份有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-119614142-A | Silicone sealant with modified heavy calcium partially substituted for nano calcium carbonate and preparation method thereof | 湖北兴发化工集团股份有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-113164361-A | Personal care compositions | 高露洁-棕榄公司 | 2021-07-23 | — | — | CN | disclosed |