Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22627146 | 0.79 | ALOX5 (0.46) | ALOX5L3MBTL1MGLLHSD17B10ALDH1A1 | |
| SCHEMBL28644643 | 0.77 | ADRB1 (0.44) | ADRB1ALOX5L3MBTL1MGLLMAPT | |
| SCHEMBL13724258 | 0.71 | ALOX5 (0.49) | ADRB1ALOX5L3MBTL1HSP90AA1MGLL | |
| SCHEMBL15507872 | 0.69 | ADRB1 (0.61) | ADRB1ALOX5L3MBTL1HSP90AA1MGLL | |
| SCHEMBL5540575 | 0.68 | ADRB1 (0.80) | ADRB1ALOX5ALDH1A1KCNH2NOTUM | |
| SCHEMBL29391951 | 0.67 | ADRB1 (1.00) | ADRB1MAPTALDH1A1KCNH2 | |
| SCHEMBL81365 | 0.67 | ADRB1 (1.00) | ADRB1MAPTALDH1A1KCNH2 | |
| SCHEMBL9022967 | 0.67 | L3MBTL1 (0.50) | ADRB1ALOX5L3MBTL1HSP90AA1MGLL | |
| SCHEMBL9715330 | 0.66 | ADRB1 (0.62) | ADRB1ALOX5L3MBTL1HSP90AA1MGLL | |
| SCHEMBL10373770 | 0.66 | ADRB1 (0.74) | ADRB1L3MBTL1MAPTALDH1A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113480485-B | 1,2, 4-triaryl-1, 2, 4-triazoles compound and synthetic method thereof | 甘肃农业大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-113480485-A | 1,2, 4-triaryl-1, 2, 4-triazoles compound and synthetic method thereof | 甘肃农业大学 | 2021-10-08 | — | — | CN | disclosed |