Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28639508 | 0.77 | ADRB1 (0.50) | ADRB1ALOX5MAPTTDP1ACHE | |
| SCHEMBL22555647 | 0.74 | ADRB1 (0.57) | ADRB1ALOX5LMNAF2ELANE | |
| SCHEMBL10615436 | 0.67 | ALOX5 (0.43) | ADRB1ALOX5LMNAF2ELANE | |
| SCHEMBL8942578 | 0.67 | ALOX5 (0.43) | ADRB1ALOX5LMNAF2ELANE | |
| SCHEMBL28030097 | 0.67 | ADRB1 (0.53) | ADRB1ALOX5LMNAF2ELANE | |
| SCHEMBL3781270 | 0.62 | ADRB1 (0.77) | ADRB1LMNAKDM4E | |
| SCHEMBL81940 | 0.61 | ADRB1 (1.00) | ADRB1LMNAKDM4ETSHR | |
| SCHEMBL6645952 | 0.61 | ADRB1 (1.00) | ADRB1LMNAKDM4ETSHR | |
| SCHEMBL2382690 | 0.60 | ALOX5 (1.00) | ALOX5F2ELANECTSGCMA1 | |
| P-Xylene SCHEMBL9289096 | 0.60 | ACHE (0.57) | ADRB1LMNAMAPTTDP1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113480485-B | 1,2, 4-triaryl-1, 2, 4-triazoles compound and synthetic method thereof | 甘肃农业大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-113480485-A | 1,2, 4-triaryl-1, 2, 4-triazoles compound and synthetic method thereof | 甘肃农业大学 | 2021-10-08 | — | — | CN | disclosed |