Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 11/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL286582 | 0.91 | KMT2A (0.38) | GABRA1GABRA5L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL286328 | 0.91 | KMT2A (0.38) | GABRA1GABRA5L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL286463 | 0.85 | ALDH1A1 (0.34) | GABRA1GABRA5L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL286460 | 0.85 | ALPL (0.43) | GABRA5L3MBTL1ALDH1A1KMT2AALPL | |
| SCHEMBL286337 | 0.83 | HCAR2 (0.39) | GABRA5L3MBTL1ALPL | |
| SCHEMBL286162 | 0.82 | GABRA5 (0.43) | GABRA1GABRA5 | |
| SCHEMBL2628060 | 0.81 | GABRA5 (0.44) | GABRA1GABRA5 | |
| SCHEMBL286372 | 0.81 | GABRA5 (0.44) | GABRA1GABRA5 | |
| SCHEMBL286080 | 0.81 | GABRA5 (0.44) | GABRA1GABRA5 | |
| SCHEMBL286160 | 0.81 | GABRA5 (0.42) | GABRA1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427455-A1 | ISOXAZOLE-PYRAZOLE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2012-03-14 | — | — | EP | disclosed |