SCHEMBL8942578

SCHEMBL8942578

Cc1ccc(N2CC=CN2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.43
ADRB1 P08588 1/20 0.39
F2 P00734 1/20 0.35
ELANE P08246 1/20 0.35
CTSG P08311 1/20 0.35
CMA1 P23946 1/20 0.35
CTRC Q99895 1/20 0.35
MAPT P10636 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
ACHE P22303 1/20 0.33
MGLL Q99685 1/20 0.33
RAB9A P51151 2/20 0.33
KDM4E B2RXH2 2/20 0.33
POLB P06746 1/20 0.33
NPC1 O15118 1/20 0.33
TP53 P04637 1/20 0.33
PKM P14618 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 1/20 0.32
HCAR1 Q9BXC0 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11401376 0.89
SCHEMBL3427816 0.79 NPSR1 (0.35) MAPTKDM4EHCAR1NOTUML3MBTL1
SCHEMBL3384925 0.79 MAPT (0.36) MAPTTDP1RAB9AKDM4EPOLB
SCHEMBL27932273 0.79 MEN1 (0.39) MAPTTDP1MGLLRAB9AKDM4E
SCHEMBL28239503 0.79 HTR3E (0.44) ADRB1MAPTMGLLRAB9APOLB
SCHEMBL44774 0.78 ALOX5 (0.39) ALOX5ADRB1RAB9ANPC1GAA
SCHEMBL13724258 0.77 ALOX5 (0.49) ALOX5ADRB1MAPTTDP1ACHE
SCHEMBL13728043 0.76 MAPT (0.50) MAPTRAB9AKDM4ENPC1TP53
SCHEMBL8600643 0.74 MEN1 (0.41) MAPTTDP1RAB9AKDM4EPOLB
SCHEMBL3382349 0.72 SIRT6 (0.47) ADRB1MAPTACHEPOLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111393367-A N-para-sulfonium salt substituted pyrazoline derivative, photocuring composition and preparation method 浙江扬帆新材料股份有限公司 2020-07-10 CN disclosed
US-RE35198-E Image forming member for electrophotography CANON KABUSHIKI KAISHA (JP) 1996-04-02 US disclosed
US-4877709-A Image forming member for electrophotography CANON KABUSHIKI KAISHA (JP) 1989-10-31 US disclosed
US-4737428-A Image forming process for electrophotography CANON KABUSHIKI KAISHA (JP) 1988-04-12 US disclosed
US-4701394-A Image forming member for elecrophotography CANON KABUSHIKI KAISHA (JP) 1987-10-20 US disclosed
US-4673628-A Image forming member for electrophotography CANON KABUSHIKI KAISHA (JP) 1987-06-16 US disclosed
US-4670369-A Image-forming member for electrophotography CANON KABUSHIKI KAISHA (JP) 1987-06-02 US disclosed
US-4613558-A Hydrogenated amorphous silicon photosensitive method for electrophotography CANON KABUSHIKI KAISHA (JP) 1986-09-23 US disclosed
US-4557990-A Hydrogenated amorphous silicon photosensitive member for electrophotography CANON KABUSHIKI KAISHA (JP) 1985-12-10 US disclosed
US-4551405-A Image forming process employing member with a depletion layer CANON KABUSHIKI KAISHA (JP) 1985-11-05 US disclosed
US-4461819-A HYDROGENATED AMORPHOUS SILICON CHARGE GENERATION LAYER CANON KABUSHIKI KAISHA (JP) 1984-07-24 US disclosed