Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28657643 | 1.00 | HTR2C (0.41) | HTR2CNAAATP53TACR1KCNH2 | |
| SCHEMBL28658169 | 0.89 | NAAA (0.40) | NAAATP53TACR1KCNH2 | |
| SCHEMBL28658170 | 0.89 | NAAA (0.40) | NAAATP53TACR1KCNH2 | |
| SCHEMBL11663631 | 0.73 | DDB1 (0.43) | — | |
| SCHEMBL28653229 | 0.71 | MMP13 (0.40) | — | |
| SCHEMBL28653227 | 0.71 | MMP13 (0.40) | — | |
| SCHEMBL28648497 | 0.70 | SLC6A3 (0.45) | — | |
| SCHEMBL28648500 | 0.70 | SLC6A3 (0.45) | — | |
| SCHEMBL28661893 | 0.70 | ADRB2 (0.41) | NAAATP53TACR1KCNH2 | |
| SCHEMBL28645234 | 0.70 | FPR1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461599-B | Process for preparing piperidone compounds | 南方科技大学 | 2024-02-09 | — | — | CN | disclosed |
| CN-113461599-A | Process for producing piperidone compound | 南方科技大学 | 2021-10-01 | — | — | CN | disclosed |