Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 3/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28658169 | 1.00 | NAAA (0.40) | NAAATACR1KCNH2MMP13MMP1 | |
| SCHEMBL28657643 | 0.89 | HTR2C (0.41) | NAAATACR1KCNH2TP53 | |
| SCHEMBL28657646 | 0.89 | HTR2C (0.41) | NAAATACR1KCNH2TP53 | |
| SCHEMBL28653229 | 0.83 | MMP13 (0.40) | MMP13MMP1NPC1RAB9AMMP2 | |
| SCHEMBL28653227 | 0.83 | MMP13 (0.40) | MMP13MMP1NPC1RAB9AMMP2 | |
| SCHEMBL28648497 | 0.82 | SLC6A3 (0.45) | MMP13MMP1HTTSMN1; SMN2MMP2 | |
| SCHEMBL28648500 | 0.82 | SLC6A3 (0.45) | MMP13MMP1HTTSMN1; SMN2MMP2 | |
| SCHEMBL28645237 | 0.81 | FPR1 (0.48) | MMP13MMP1MEN1KMT2AHSD11B1 | |
| SCHEMBL28661893 | 0.81 | ADRB2 (0.41) | NAAATACR1KCNH2MMP13MMP1 | |
| SCHEMBL30823802 | 0.81 | MMP13 (0.37) | TACR1KCNH2MMP13MMP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461599-B | Process for preparing piperidone compounds | 南方科技大学 | 2024-02-09 | — | — | CN | disclosed |
| CN-113461599-A | Process for producing piperidone compound | 南方科技大学 | 2021-10-01 | — | — | CN | disclosed |