SCHEMBL286578

SCHEMBL286578

C=CCC1OC(=O)c2ccccc21

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
HSD17B10 Q99714 1/20 0.47
SLC2A1 P11166 1/20 0.44
LMNA P02545 3/20 0.43
MEN1 O00255 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPT P10636 1/20 0.43
CYP2C9 P11712 1/20 0.43
HPGD P15428 1/20 0.43
CYP2C19 P33261 1/20 0.43
KMT2A Q03164 1/20 0.43
RECQL P46063 1/20 0.43
KDM4E B2RXH2 1/20 0.41
TSHR P16473 1/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8931106 1.00 ALDH1A1 (0.47) ALDH1A1HSD17B10SLC2A1LMNAMEN1
SCHEMBL8817632 1.00 ALDH1A1 (0.47) ALDH1A1HSD17B10SLC2A1LMNAMEN1
Ammonia Solution, Strong SCHEMBL28389948 0.98 ALDH1A1 (0.46) ALDH1A1HSD17B10SLC2A1LMNAMEN1
Piperidine SCHEMBL28556095 0.87 LMNA (0.44) ALDH1A1HSD17B10SLC2A1LMNAMEN1
SCHEMBL7722439 0.79 ALDH1A1 (0.54) ALDH1A1HSD17B10LMNAMEN1CYP1A2
SCHEMBL14965898 0.79 ALDH1A1 (0.54) ALDH1A1HSD17B10LMNAMEN1CYP1A2
SCHEMBL16209547 0.79 ALDH1A1 (0.54) ALDH1A1HSD17B10LMNAMEN1CYP1A2
SCHEMBL9879491 0.79 ALDH1A1 (0.44) ALDH1A1HSD17B10LMNAMEN1CYP1A2
SCHEMBL28352710 0.79 ALDH1A1 (0.45) ALDH1A1HSD17B10LMNAMEN1CYP1A2
SCHEMBL15094402 0.79 SLC2A1 (0.43) ALDH1A1SLC2A1MAPTKMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118373791-A Allyl phthalide compound and preparation method and application thereof 南京工业大学 2024-07-23 CN claimed
CN-117897055-A Method for reducing abnormal odor 奇华顿股份有限公司 2024-04-16 CN claimed
CN-117860736-A Butylphthalide composition and application thereof in treating testicular ischemia reperfusion 延安大学咸阳医院有限公司 2024-04-12 CN claimed
US-11684559-B2 Topical cosmetic treatment of skin and scalp and corresponding active ingredient based on an extract of Apium graveolens SEDERMA (FR) 2023-06-27 US claimed
CN-111670027-B Cosmetic use of cyclic peptides 赛德玛公司 2023-06-06 CN claimed
CN-110698445-B 3-amine alkyl phthalide compound, preparation method and application thereof 四川大学 2023-05-12 CN claimed
CN-115554289-A Pharmaceutical active composition containing butylphthalide and preparation method thereof 成都施贝康生物医药科技有限公司 2023-01-03 CN claimed
CN-109789080-B Alkyl phthalides for use in cosmetic treatment of nails 赛德玛公司 2022-06-24 CN claimed
US-20220062139-A1 TOPICAL COSMETIC TREATMENT OF SKIN AND SCALP AND CORRESPONDING ACTIVE INGREDIENT BASED ON AN EXTRACT OF APIUM GRAVEOLENS SEDERMA (FR) 2022-03-03 US claimed
US-11166897-B2 Topical cosmetic treatment of scalp and corresponding active ingredient based on an extract of Apium graveolens SEDERMA (FR) 2021-11-09 US claimed
US-20180078481-A1 TOPICAL COSMETIC TREATMENT OF SKIN AND SCALP AND CORRESPONDING ACTIVE INGREDIENT BASED ON AN EXTRACT OF APIUM GRAVEOLENS SEDERMA (FR) 2018-03-22 US claimed
EP-3277254-A1 TOPICAL COSMETIC TREATMENT OF SKIN AND SCALP AND CORRESPONDING ACTIVE INGREDIENT BASED ON AN EXTRACT OF APIUM GRAVEOLENS SEDERMA (FR) 2018-02-07 EP claimed
CN-107396627-A The processing of the local beauty of skin and scalp and the accordingly active component based on Herba Apii graveolentis extract 赛德玛公司 2017-11-24 CN claimed
WO-2016157073-A1 TOPICAL COSMETIC TREATMENT OF SKIN AND SCALP AND CORRESPONDING ACTIVE INGREDIENT BASED ON AN EXTRACT OF APIUM GRAVEOLENS SEDERMA (FR) 2016-10-06 WO claimed
US-20150045564-A1 Cu-MEDIATED ANNULATION FOR THE EFFECTIVE SYNTHESIS OF 3-SUBSTITUTED PHTHALIDES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-02-12 US claimed
WO-2013102935-A2 Cu-MEDIATED ANNULATION FOR THE EFFECTIVE SYNTHESIS OF 3-SUBSTITUTED PHTHALIDES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2013-07-11 WO claimed
US-20050087725-A1 Thermochromic tire KANAKKANATT SEBASTINA V (US) 2005-04-28 US claimed
US-6326006-B1 ACCELERATING BLOOD CIRCULATION, BODY WARMING AND RETENTION OF WARMTH; COMPRISES ALKYL PHTHALIDE, ALKOXY PHTHALIDE, ALKYLIDENE PHTHALIDE OR MIXTURE KAO CORPORATION (JP) 2001-12-04 US claimed
EP-0357081-B1 Bathing preparation KAO CORP (JP) 1995-01-04 EP claimed
EP-0357081-A2 Bathing preparation Kao Corporation (JP) 1990-03-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180078481-A1 TOPICAL COSMETIC TREATMENT OF SKIN AND SCALP AND CORRESPONDING ACTIVE INGREDIENT BASED ON AN EXTRACT OF APIUM GRAVEOLENS SAP18, CYP51A1, NAA10 ALDH1A1 863/4885HSD17B10 29/4885SLC2A1 4606/4885
US-20220062139-A1 TOPICAL COSMETIC TREATMENT OF SKIN AND SCALP AND CORRESPONDING ACTIVE INGREDIENT BASED ON AN EXTRACT OF APIUM GRAVEOLENS SAP18, CYP51A1, NAA10 ALDH1A1 863/4885HSD17B10 29/4885SLC2A1 4606/4885
US-11684559-B2 Topical cosmetic treatment of skin and scalp and corresponding active ingredient based on an extract of Apium graveolens SAP18, CYP51A1, NAA10 ALDH1A1 863/4885HSD17B10 29/4885SLC2A1 4606/4885
US-20150045564-A1 Cu-MEDIATED ANNULATION FOR THE EFFECTIVE SYNTHESIS OF 3-SUBSTITUTED PHTHALIDES SOD1, AOC2, SOD3 ALDH1A1 97/4885HSD17B10 753/4885SLC2A1 3834/4885
US-11166897-B2 Topical cosmetic treatment of scalp and corresponding active ingredient based on an extract of Apium graveolens SAP18, CYP51A1, NASP ALDH1A1 933/4885HSD17B10 22/4885SLC2A1 4737/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.