Bromide

Bromide

SCHEMBL8775234

CCCCCCCCCCCCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-]

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.56
TRAP1 Q12931 2/20 0.46
CHRNA7 P36544 7/20 0.45
ALDH1A1 P00352 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
TSHR P16473 1/20 0.44
CYP2C19 P33261 1/20 0.44
DNM1 Q05193 2/20 0.43
CSNK1E P49674 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL286882 1.00 HIF1A (0.56) HIF1ATRAP1CHRNA7ALDH1A1CYP1A2
Bromide SCHEMBL2446607 1.00 HIF1A (0.56) HIF1ATRAP1CHRNA7ALDH1A1CYP1A2
Bromide SCHEMBL678415 1.00 HIF1A (0.56) HIF1ATRAP1CHRNA7ALDH1A1CYP1A2
Bromide SCHEMBL362235 1.00 HIF1A (0.56) HIF1ATRAP1CHRNA7ALDH1A1CYP1A2
Bromide SCHEMBL1866839 1.00 HIF1A (0.56) HIF1ATRAP1CHRNA7ALDH1A1CYP1A2
Bromide SCHEMBL7759526 1.00 HIF1A (0.56) HIF1ATRAP1CHRNA7ALDH1A1CYP1A2
Bromide SCHEMBL635580 1.00 HIF1A (0.56) HIF1ATRAP1CHRNA7ALDH1A1CYP1A2
Bromide SCHEMBL164301 1.00 HIF1A (0.56) HIF1ATRAP1CHRNA7ALDH1A1CYP1A2
Bromide SCHEMBL2979400 1.00 HIF1A (0.56) HIF1ATRAP1CHRNA7ALDH1A1CYP1A2
Bromide SCHEMBL1963378 1.00 HIF1A (0.56) HIF1ATRAP1CHRNA7ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10588962-B2 Carbohydrate-glycolipid conjugate vaccines MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2020-03-17 US disclosed
US-10052373-B2 Protein and peptide-free synthetic vaccines against Streptococcus pneumoniae type 3 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2018-08-21 US disclosed
EP-3046587-B1 PROTEIN AND PEPTIDE-FREE SYNTHETIC VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE TYPE 3 MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WSS (DE) 2018-01-31 EP disclosed
US-20160279224-A1 PROTEIN AND PEPTIDE-FREE SYNTHETIC VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE TYPE 3 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2016-09-29 US disclosed
EP-3046587-A1 PROTEIN AND PEPTIDE-FREE SYNTHETIC VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE TYPE 3 Max-Planck-Gesellschaft zur Förderung der Wissenschaften (DE) 2016-07-27 EP disclosed
US-20150238597-A1 CARBOHYDRATE-GLYCOLIPID CONJUGATE VACCINES MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2015-08-27 US disclosed
EP-2827899-B1 POLYSACCHARIDE ANTIGEN-GLYCOLIPID CONJUGATE VACCINES MAX PLANCK GES ZUR FÖRDERUNG DER WISSENSCHAFTEN E V (DE) 2015-08-05 EP disclosed
WO-2015040140-A1 PROTEIN AND PEPTIDE-FREE SYNTHETIC VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE TYPE 3 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2015-03-26 WO disclosed
EP-2851092-A1 Protein and peptide-free synthetic vaccines against streptococcus pneumoniae type 3 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2015-03-25 EP disclosed
EP-2827899-A1 CARBOHYDRATE-GLYCOLIPID CONJUGATE VACCINES Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2015-01-28 EP disclosed
US-4968851-A AGAINST ARTHROPODS AND NEMATODES BAYER AKTIENGESELLSCHAFT (DE) 1990-11-06 US disclosed
EP-0247484-B1 HALOGEN OLEFINES BAYER AG (DE) 1990-08-16 EP disclosed
US-4839390-A FOR SOIL TREATMENT; AGRICULTURE BAYER AKTIENGESELLSCHAFT (DE) 1989-06-13 US disclosed
US-4775662-A ASTHMA TREATMENT, ANTIALLERGENS, BRONCHODILATOR AGENTS SMITHKLINE BECKMAN CORPORATION (US) 1988-10-04 US disclosed
EP-0248597-A2 Phospholipase A2 inhibitors and methods of synthesis ORTHO PHARMACEUTICAL CORPORATION (US) 1987-12-09 EP disclosed
EP-0247484-A1 Halogen olefines BAYER AG (DE) 1987-12-02 EP disclosed
EP-0121350-B1 SUBSTITUTED UNSATURATED MERCAPTOCARBOXYLIC ACIDS AND DERIVATIVES AS LEUKOTRIENE ANTAGONISTS SMITHKLINE BECKMAN CORPORATION (US) 1987-05-13 EP disclosed
US-4533747-A ANTIASTHMATICS, ANTIHISTAMINES SMITHKLINE BECKMAN CORPORATION (US) 1985-08-06 US disclosed
EP-0121350-A2 Substituted unsaturated mercaptocarboxylic acids and derivatives as leukotriene antagonists SMITHKLINE BECKMAN CORPORATION (US) 1984-10-10 EP disclosed
US-4346040-A Process for converting an aldehyde into an alkene, in particular furfural into furfurylidenes AGRIFURANE S.A. (FR) 1982-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150238597-A1 CARBOHYDRATE-GLYCOLIPID CONJUGATE VACCINES STT3B, STT3A, DDOST HIF1A 4077/4885TRAP1 1937/4885CHRNA7 3808/4885
US-10052373-B2 Protein and peptide-free synthetic vaccines against Streptococcus pneumoniae type 3 STT3A, DDOST, LGALS3BP HIF1A 3156/4885TRAP1 2716/4885CHRNA7 3443/4885
US-20160279224-A1 PROTEIN AND PEPTIDE-FREE SYNTHETIC VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE TYPE 3 STT3A, DDOST, LGALS3BP HIF1A 3156/4885TRAP1 2716/4885CHRNA7 3443/4885
US-10588962-B2 Carbohydrate-glycolipid conjugate vaccines STT3B, STT3A, DDOST HIF1A 4077/4885TRAP1 1937/4885CHRNA7 3808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.