SCHEMBL28688705

SCHEMBL28688705

CCCCCO[SiH](OCCCCC)C(C)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.43
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
LMNA P02545 1/20 0.42
GPR88 Q9GZN0 1/20 0.39
PTPN1 P18031 1/20 0.39
TSHR P16473 2/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPK1 P28482 1/20 0.39
HTR2A P28223 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL706389 0.95 LTA4H (0.43) LTA4HNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL706074 0.87 TAAR1 (0.38) LMNAGPR88TSHRHTR2A
SCHEMBL22661009 0.84 LMNA (0.48) LTA4HNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL19809149 0.80 NPC1 (0.45) LTA4HNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL115878 0.79 TAAR1 (0.40) LMNAHTR2A
SCHEMBL706283 0.77 LTA4H (0.41) LTA4HNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL17937761 0.77 KDM4E (0.37) NPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL17937572 0.77 ADRB2 (0.38) NPC1RAB9ASMN1; SMN2LMNA
SCHEMBL702250 0.76 LTA4H (0.40) LTA4HNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL17937608 0.76 KMT2A (0.44) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108250754-B Silicon-containing resin composition, silicon-containing resin film, silica film, light-emitting display element panel, and light-emitting display device 东京应化工业株式会社 2022-01-25 CN disclosed