Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052104 | 0.87 | NNMT (0.48) | NNMTMEN1KMT2AKIF11 | |
| SCHEMBL15881082 | 0.76 | ALDH1A1 (0.41) | NNMTMEN1KMT2A | |
| SCHEMBL28941021 | 0.76 | NNMT (0.44) | NNMTMEN1KMT2AKIF11 | |
| SCHEMBL28572641 | 0.73 | NNMT (0.38) | NNMTMEN1KMT2A | |
| SCHEMBL28574759 | 0.72 | NNMT (0.37) | NNMTMEN1KMT2A | |
| SCHEMBL20639594 | 0.71 | NNMT (0.41) | NNMTMEN1KMT2A | |
| SCHEMBL19667223 | 0.68 | MEN1 (0.33) | NNMTMEN1KMT2AKIF11 | |
| SCHEMBL25381420 | 0.68 | SIRT6 (0.39) | NNMTMEN1KMT2A | |
| SCHEMBL10847338 | 0.68 | P2RX7 (0.43) | NNMTMEN1KMT2AKIF11 | |
| SCHEMBL8539378 | 0.68 | MEN1 (0.36) | NNMTMEN1KMT2AKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117903169-A | Pan-KRAS inhibitor compound | 杭州阿诺生物医药科技有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-107921044-B | GLS1 inhibitors for the treatment of disease | 德州大学系统董事会 | 2022-01-21 | — | — | CN | disclosed |