SCHEMBL8539378

SCHEMBL8539378

NC(=O)Oc1ccnnn1

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
NNMT P40261 1/20 0.32
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27419554 0.80 LMNA (0.36)
SCHEMBL4052104 0.78 NNMT (0.48) MEN1KMT2ANNMTKIF11
SCHEMBL27725288 0.77 THRB (0.38) MEN1KMT2A
SCHEMBL10847338 0.76 P2RX7 (0.43) MEN1KMT2ANNMTKIF11
SCHEMBL10665799 0.76 ALDH1A1 (0.38) KMT2A
SCHEMBL29165581 0.74
SCHEMBL28280316 0.74
SCHEMBL28953936 0.74 KMT2A (0.45) MEN1KMT2A
Tromethamine SCHEMBL6235066 0.72
SCHEMBL27696080 0.72 KMT2A (0.42) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0540697-B1 SULFONYLUREAS CIBA GEIGY AG (CH) 1998-06-03 EP claimed
EP-0626958-A1 SULFONYLUREAS AS HERBICIDES CIBA-GEIGY AG (CH) 1994-12-07 EP claimed
WO-1993017016-A1 SULFONYLUREAS AS HERBICIDES CIBA-GEIGY AG (CH) 1993-09-02 WO claimed
EP-0540697-A1 NOVEL SULFONYLUREAS Novartis AG (CH) 1993-05-12 EP claimed
WO-1992016522-A1 NOVEL SULFONYLUREAS CIBA-GEIGY AG (CH) 1992-10-01 WO claimed
EP-0246984-A2 Sulfonyl urea herbicides, their preparation, compositions containing them and their use RHONE-POULENC AGROCHIMIE (FR) 1987-11-25 EP claimed
EP-0540697-B1 SULFONYLUREAS CIBA GEIGY AG (CH) 1998-06-03 EP disclosed
US-5625071-A HERBICIDES CIBA-GEIGY CORPORATION (US) 1997-04-29 US disclosed
US-5403814-A Preemergence and postemergence herbicides CIBA-GEIGY CORPORATION (US) 1995-04-04 US disclosed
EP-0626958-A1 SULFONYLUREAS AS HERBICIDES CIBA-GEIGY AG (CH) 1994-12-07 EP disclosed
US-5342823-A Herbicides, plant growth regulators CIBA-GEIGY CORPORATION (US) 1994-08-30 US disclosed
WO-1993017016-A1 SULFONYLUREAS AS HERBICIDES CIBA-GEIGY AG (CH) 1993-09-02 WO disclosed
WO-1992016522-A1 NOVEL SULFONYLUREAS CIBA-GEIGY AG (CH) 1992-10-01 WO disclosed
EP-0246984-A2 Sulfonyl urea herbicides, their preparation, compositions containing them and their use RHONE-POULENC AGROCHIMIE (FR) 1987-11-25 EP disclosed