Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.31 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.31 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.31 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.31 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28690449 | 0.87 | NNMT (0.40) | NNMTKMT2AMEN1KIF11 | |
| SCHEMBL15881082 | 0.87 | ALDH1A1 (0.41) | NNMTKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28941021 | 0.87 | NNMT (0.44) | NNMTKMT2AMEN1KIF11MKNK1 | |
| SCHEMBL28572641 | 0.84 | NNMT (0.38) | NNMTKMT2AMEN1 | |
| SCHEMBL28574759 | 0.82 | NNMT (0.37) | NNMTKMT2AMEN1 | |
| SCHEMBL8539378 | 0.78 | MEN1 (0.36) | NNMTKMT2AMEN1KIF11 | |
| SCHEMBL10847338 | 0.78 | P2RX7 (0.43) | NNMTKMT2AMEN1KIF11MKNK1 | |
| SCHEMBL29177262 | 0.77 | CYP1A2 (0.47) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10768300 | 0.75 | MEN1 (0.52) | KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL22557500 | 0.73 | KDM4E (0.44) | NNMTKMT2AMEN1MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044035-A1 | PROCESS FOR THE COVALENT COUPLING OF TWO MOLECULES BY MEANS OF A DIELS-ALDER REACTION WITH INVERSE ELECTRON REQUIREMENT | Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts (DE) | 2009-04-08 | — | — | EP | claimed |
| WO-2007144200-A1 | PROCESS FOR THE COVALENT COUPLING OF TWO MOLECULES BY MEANS OF A DIELS-ALDER REACTION WITH INVERSE ELECTRON REQUIREMENT | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 2007-12-21 | — | — | WO | claimed |
| EP-1867638-A1 | Procedure for the Conection of two Molecules via Diels-Alder Reactions with Inverse Electron Demand | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 2007-12-19 | — | — | EP | claimed |