Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 6/20 | 0.69 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.68 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.68 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.68 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.68 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.68 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | HTR1B | P28222 | 4/20 | 0.68 |
| ▸ | RAD52 | P43351 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | PTGIR | P43119 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3178397 | 0.84 | MAOA (0.69) | HTR1DTAAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL4037274 | 0.83 | HTR1D (0.71) | HTR1DTAAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL953972 | 0.81 | RAD52 (0.82) | HTR1DTAAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL9393147 | 0.81 | HTR1D (0.69) | HTR1DTAAR1ADRA2AADRA2BADRA2C | |
| Tolazoline SCHEMBL34961 | 0.81 | TAAR1 (1.00) | HTR1DTAAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL10846015 | 0.81 | TAAR1 (0.72) | HTR1DTAAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL27738615 | 0.81 | HTR1D (0.63) | HTR1DTAAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL953553 | 0.81 | TAAR1 (0.60) | HTR1DTAAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL8154758 | 0.81 | HTR1D (1.00) | HTR1DTAAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL7007927 | 0.80 | HTR1D (0.57) | HTR1DTAAR1ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230312524-A1 | ALPHA1A-ADRENERGIC RECEPTOR AGONISTS AND METHODS OF USE | CURASEN THERAPEUTICS, INC. | 2023-10-05 | — | — | US | disclosed |
| WO-2010016620-A1 | SURFACE TREATING AGENT FOR COPPER OR COPPER ALLOY AND USE THEREOF | SHIKOKU CHEMICALS CORPORATION (JP) | 2010-02-11 | — | — | WO | disclosed |
| US-5070086-A | ANTIALLERGY, ANTIINFLAMMATORY, ANTIPSORIASIS | SCHERING CORPORATION (US) | 1991-12-03 | — | — | US | disclosed |
| EP-0325048-A1 | Imidazo- and pyrimido-quinoline, naphthyridine and pyridopyrazine compounds | SCHERING CORPORATION (US) | 1989-07-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230312524-A1 | ALPHA1A-ADRENERGIC RECEPTOR AGONISTS AND METHODS OF USE | ADRA1A, ADRB1, ADRA1D | HTR1D 47/4885TAAR1 26/4885ADRA2A 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.