Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.82 |
| ▸ | HTR1D | P28221 | 6/20 | 0.69 |
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.68 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.68 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.68 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.68 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.68 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | HTR1B | P28222 | 4/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | PTGIR | P43119 | 1/20 | 0.54 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4036373 | 0.89 | RAD52 (0.68) | RAD52HTR1DTAAR1ADRA2AADRA2B | |
| SCHEMBL4629569 | 0.84 | RAD52 (0.61) | RAD52HTR1DTAAR1ADRA2AADRA2B | |
| SCHEMBL4032937 | 0.84 | MAOA (0.69) | RAD52HTR1DTAAR1ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL4711895 | 0.84 | MAOA (0.69) | RAD52HTR1DTAAR1ADRA2AADRA2B | |
| SCHEMBL4037274 | 0.83 | HTR1D (0.71) | RAD52HTR1DTAAR1ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL4711894 | 0.82 | MAOA (0.67) | RAD52HTR1DTAAR1ADRA2AADRA2B | |
| SCHEMBL9393147 | 0.81 | HTR1D (0.69) | RAD52HTR1DTAAR1ADRA2AADRA2B | |
| SCHEMBL2869241 | 0.81 | HTR1D (0.69) | RAD52HTR1DTAAR1ADRA2AADRA2B | |
| Tolazoline SCHEMBL34961 | 0.81 | TAAR1 (1.00) | RAD52HTR1DTAAR1ADRA2AADRA2B | |
| SCHEMBL10846015 | 0.81 | TAAR1 (0.72) | RAD52HTR1DTAAR1ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1635821-B1 | 4-BROMO-5-(2-CHLORO-BENZOYLAMINO)-1H-PYRAZOLE-3-CARBOXYLIC ACID (PHENYL)AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ELAN PHARM INC (US) | 2009-07-08 | — | — | EP | claimed |
| CN-101374516-A | Use of substituted 2-imidazole of imidazoline derivatives | HOFFMANN LA ROCHE (CH) | 2009-02-25 | — | — | CN | claimed |
| US-20070197621-A1 | Method for the treatment of CNS disorders with substituted 2-imidazoles or imidazole derivatives | F. HOFFMANN-LA ROCHE AG, A SWISS COMPANY (CH) | 2007-08-23 | — | — | US | claimed |
| US-20070123531-A1 | 4-Bromo-5-(2-chloro-benzoylamino)-1h-pyrazole-3-carboxylic acid (phenyl) amide derivatives and related compounds as bradykinin b1 receptor antagonists for the treatment of inflammatory diseases | ELAN PHARMACEUTICALS, INC. | 2007-05-31 | — | — | US | claimed |
| EP-1635821-A2 | 4-BROMO-5-(2-CHLORO-BENZOYLAMINO)-1H-PYRAZOLE-3-CARBOXYLIC ACID (PHENYL)AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | Elan Pharmaceuticals, Inc. (US) | 2006-03-22 | — | — | EP | claimed |
| US-20050032868-A1 | Selected substituted pyrazole derivatives and related compounds as bradykinin B1 receptor antagonists | ELAN PHARMACEUTICALS, INC. | 2005-02-10 | — | — | US | claimed |
| WO-2004099155-A2 | 4-BROMO-5-(2-CHLORO-BENZOYLAMINO)-1H-PYRAZOLE-3-CARBOXYLIC ACID (PHENYL) AMIDE DERIVATES AND RELATED COMPOUNDS AS BRADYKININ B1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMATORY DISEASES | ELAN PHARMACEUTICALS, INC. (US) | 2004-11-18 | — | — | WO | claimed |
| US-20250387373-A1 | SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS | OHIO STATE INNOVATION FOUNDATION (US) | 2025-12-25 | — | — | US | disclosed |
| US-12390449-B2 | Substituted 2-aminobenzimidazoles analogs as antibiofilm agents | OHIO STATE INNOVATION FOUNDATION (US) | 2025-08-19 | — | — | US | disclosed |
| EP-4590938-A1 | INTER-TURBINE CASING FOR A TURBINE ENGINE, TURBINE ENGINE ASSEMBLY, TURBINE ENGINE AND METHOD FOR POSITIONING A SPLITTER VANE WITHIN AN INTER-TURBINE CASING | SAFRAN AIRCRAFT ENGINES (FR) | 2025-07-30 | — | — | EP | disclosed |
| CN-119243160-A | Novel alkaline copper CMP polishing solution and preparation method thereof | 河北工业大学 | 2025-01-03 | — | — | CN | disclosed |
| CN-119243160-A | Novel alkaline copper CMP polishing solution and preparation method thereof | 河北工业大学 | 2025-01-03 | — | — | CN | disclosed |
| US-20240156788-A1 | SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS | NORTH CAROLINA STATE UNIVERSITY | 2024-05-16 | — | — | US | disclosed |
| US-20070123531-A1 | 4-Bromo-5-(2-chloro-benzoylamino)-1h-pyrazole-3-carboxylic acid (phenyl) amide derivatives and related compounds as bradykinin b1 receptor antagonists for the treatment of inflammatory diseases | ELAN PHARMACEUTICALS, INC. | 2007-05-31 | — | — | US | disclosed |
| EP-1635821-A2 | 4-BROMO-5-(2-CHLORO-BENZOYLAMINO)-1H-PYRAZOLE-3-CARBOXYLIC ACID (PHENYL)AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | Elan Pharmaceuticals, Inc. (US) | 2006-03-22 | — | — | EP | disclosed |
| US-20050032868-A1 | Selected substituted pyrazole derivatives and related compounds as bradykinin B1 receptor antagonists | ELAN PHARMACEUTICALS, INC. | 2005-02-10 | — | — | US | disclosed |
| WO-2004099155-A2 | 4-BROMO-5-(2-CHLORO-BENZOYLAMINO)-1H-PYRAZOLE-3-CARBOXYLIC ACID (PHENYL) AMIDE DERIVATES AND RELATED COMPOUNDS AS BRADYKININ B1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMATORY DISEASES | ELAN PHARMACEUTICALS, INC. (US) | 2004-11-18 | — | — | WO | disclosed |
| EP-0331507-B1 | POLYVINYL CHLORIDE PLASTISOL COMPOSITION | ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) | 1993-05-19 | — | — | EP | disclosed |
| US-4977201-A | Blended with modified epoxy resin, blocked isocyanate, latent curing for resin as tackifier, automobile undercoatings | ASAHI DENKA KOGYO K.K. (JP) | 1990-12-11 | — | — | US | disclosed |
| EP-0331507-A1 | Polyvinyl chloride plastisol composition | ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) | 1989-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123531-A1 | 4-Bromo-5-(2-chloro-benzoylamino)-1h-pyrazole-3-carboxylic acid (phenyl) amide derivatives and related compounds as bradykinin b1 receptor antagonists for the treatment of inflammatory diseases | BDKRB1, BDKRB2, LTB4R | RAD52 3545/4885HTR1D 347/4885TAAR1 109/4885 |
| US-12390449-B2 | Substituted 2-aminobenzimidazoles analogs as antibiofilm agents | ITGB3, ITGB2, ITGAM | RAD52 4312/4885HTR1D 2458/4885TAAR1 2718/4885 |
| US-20250387373-A1 | SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS | ITGB3, CFTR, Q6ZSR9 | RAD52 4361/4885HTR1D 109/4885TAAR1 1224/4885 |
| US-20050032868-A1 | Selected substituted pyrazole derivatives and related compounds as bradykinin B1 receptor antagonists | BDKRB1, BDKRB2, BRS3 | RAD52 2927/4885HTR1D 231/4885TAAR1 351/4885 |
| US-20070197621-A1 | Method for the treatment of CNS disorders with substituted 2-imidazoles or imidazole derivatives | GPR119, PER2, MTNR1B | RAD52 4584/4885HTR1D 28/4885TAAR1 117/4885 |
| US-20240156788-A1 | SUBSTITUTED 2-AMINOBENZIMIDAZOLES ANALOGS AS ANTIBIOFILM AGENTS | ITGB3, ITGB2, ITGAM | RAD52 4312/4885HTR1D 2458/4885TAAR1 2718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.