Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TSPO | P30536 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | PTGIR | P43119 | 1/20 | 0.45 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28696202 | 1.00 | LMNA (0.53) | LMNAALDH1A1PTGDR2HDAC1HDAC6 | |
| SCHEMBL13687190 | 0.91 | LMNA (0.62) | LMNAALDH1A1PTGDR2L3MBTL1TSHR | |
| SCHEMBL21591698 | 0.86 | CCR6 (0.44) | LMNAALDH1A1L3MBTL1TSHRMAPK1 | |
| SCHEMBL21591622 | 0.86 | PIN1 (0.46) | LMNAALDH1A1L3MBTL1TSPOHSD17B10 | |
| SCHEMBL16553793 | 0.84 | ALDH1A1 (0.44) | LMNAALDH1A1HDAC1HDAC6TSHR | |
| SCHEMBL16665613 | 0.83 | ALDH1A1 (0.58) | LMNAALDH1A1PTGDR2L3MBTL1TSHR | |
| SCHEMBL1901573 | 0.83 | CHRNB2 (0.53) | LMNAALDH1A1HDAC1HDAC6L3MBTL1 | |
| SCHEMBL27364470 | 0.82 | CCR6 (0.55) | LMNAALDH1A1L3MBTL1TSHRMAPK1 | |
| SCHEMBL7367394 | 0.82 | CRHBP (0.58) | LMNAALDH1A1NPC1 | |
| SCHEMBL16553708 | 0.81 | CCR6 (0.41) | LMNAALDH1A1HDAC1HDAC6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071560-B | Thienopyridine carboxamides as ubiquitin-specific protease inhibitors | 瓦洛健康公司 | 2022-01-14 | — | — | CN | disclosed |