SCHEMBL28697235

SCHEMBL28697235

COC(=O)Oc1ccc(CSCc2ccccc2)c(C)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
LMNA P02545 4/20 0.43
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
HTT P42858 4/20 0.42
ALDH1A1 P00352 3/20 0.42
RAB9A P51151 2/20 0.42
GLA P06280 1/20 0.41
MTNR1A P48039 1/20 0.39
MTNR1B P49286 1/20 0.39
CYP1A2 P05177 1/20 0.39
PDCD1 Q15116 1/20 0.39
CD274 Q9NZQ7 1/20 0.39
S1PR1 P21453 1/20 0.39
S1PR5 Q9H228 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28687524 0.88 KDM4E (0.44) MEN1KMT2ALMNAMAPTKDM4E
SCHEMBL28698223 0.88 MEN1 (0.45) MEN1KMT2ALMNAMAPTKDM4E
SCHEMBL28697234 0.84 ALDH1A1 (0.54) MEN1KMT2ALMNAMAPTKDM4E
SCHEMBL9728462 0.83 RAB9A (0.52) LMNAMAPTKDM4EL3MBTL1HTT
SCHEMBL20421985 0.79 HTT (0.48) MEN1KMT2ALMNAMAPTKDM4E
SCHEMBL28698222 0.75 LMNA (0.50) MEN1KMT2ALMNAMAPTKDM4E
SCHEMBL31038960 0.74 HTT (0.44) LMNAL3MBTL1HTTALDH1A1RAB9A
Trifluoromethanesulfonic Acid SCHEMBL20421987 0.73 HTT (0.44) LMNAMAPTKDM4EL3MBTL1HTT
SCHEMBL28700543 0.73 ALOX5 (0.46) MEN1KMT2ALMNAMAPTKDM4E
SCHEMBL9220921 0.73 LMNA (0.49) KMT2ALMNAMAPTKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109661601-B Polarizing plate and method for manufacturing same 住友化学株式会社 2022-02-01 CN disclosed