SCHEMBL20421985

SCHEMBL20421985

COC(=O)Oc1ccc(CSCc2ccccc2)cc1.CS(=O)(=O)O

nearest known ligand 0.48

Known targets — ChEMBL curated mechanism

ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTT P42858 3/20 0.48
▸ RAB9A P51151 2/20 0.48
▸ LMNA P02545 2/20 0.48
▸ L3MBTL1 Q9Y468 2/20 0.43
▸ ACE P12821 1/20 0.43
▸ EPHX1 P07099 1/20 0.42
▸ GAA P10253 2/20 0.42
▸ NPC1 O15118 1/20 0.42
▸ TAAR1 Q96RJ0 1/20 0.42
▸ KDM4E B2RXH2 3/20 0.41
▸ MAPT P10636 2/20 0.41
▸ ALDH1A1 P00352 2/20 0.41
▸ PKM P14618 1/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ TP53 P04637 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ PPARG P37231 1/20 0.41
▸ PPARA Q07869 1/20 0.41
▸ MMP1 P03956 1/20 0.41
▸ MMP2 P08253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9728462 0.94 RAB9A (0.52) HTTRAB9ALMNAL3MBTL1ACE
SCHEMBL31038960 0.92 HTT (0.44) HTTRAB9ALMNAL3MBTL1ACE
Trifluoromethanesulfonic Acid SCHEMBL20421987 0.91 HTT (0.44) HTTRAB9ALMNAL3MBTL1ACE
SCHEMBL9220921 0.83 LMNA (0.49) HTTRAB9ALMNAL3MBTL1ACE
SCHEMBL28697234 0.81 ALDH1A1 (0.54) HTTLMNAL3MBTL1KDM4EMAPT
SCHEMBL9222914 0.79 LMNA (0.50) HTTRAB9ALMNAL3MBTL1NPC1
SCHEMBL28697235 0.79 MEN1 (0.45) HTTRAB9ALMNAL3MBTL1GAA
SCHEMBL28973261 0.79 ELANE (0.56) HTTRAB9ALMNAGAANPC1
Trifluoromethanesulfonic Acid SCHEMBL29634745 0.78 PPARG (0.48) HTTRAB9ALMNAL3MBTL1GAA
SCHEMBL20421986 0.77 MMP1 (0.43) RAB9AACEGAANPC1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114730132-B Curable resin composition, cured film, laminate, method for producing cured film, semiconductor device, and resin 富士胶片株式会社 2025-05-09 — — CN disclosed
CN-114761466-B Curable resin composition, cured film, laminate, method for producing cured film, semiconductor device, and resin 富士胶片株式会社 2024-12-10 — — CN disclosed
CN-114008527-B Curable resin composition, cured film, laminate, method for producing cured film, semiconductor device, and polyimide or polyimide precursor 富士胶片株式会社 2024-11-01 — — CN disclosed
CN-116113884-A Method for producing cured product, method for producing laminate, and method for producing electronic device 富士胶片株式会社 2023-05-12 — — CN disclosed
CN-115768832-A Resin composition, method for producing same, and method for producing composition for pattern formation 富士胶片株式会社 2023-03-07 — — CN disclosed
CN-115038755-A Curable resin composition, resin film, cured film, laminate, method for producing cured film, and semiconductor device 富士胶片株式会社 2022-09-09 — — CN disclosed
CN-114730145-A Pattern forming method, photocurable resin composition, method for producing laminate, and method for producing electronic device 富士胶片株式会社 2022-07-08 — — CN disclosed
CN-108700836-B Method for manufacturing laminate and method for manufacturing semiconductor device 富士胶片株式会社 2022-06-28 — — CN disclosed
CN-114514470-A Pattern forming method, photosensitive resin composition, method for manufacturing laminate, and method for manufacturing semiconductor device 富士胶片株式会社 2022-05-17 — — CN disclosed
US-10780679-B2 Laminate, method for manufacturing laminate, semiconductor device, and method for manufacturing the semiconductor device FUJIFILM CORPORATION (JP) 2020-09-22 — — US disclosed
EP-3339352-B1 RESIN, COMPOSITION, CURED FILM, METHOD FOR MANUFACTURING CURED FILM AND SEMICONDUCTOR DEVICE FUJIFILM CORP (JP) 2020-09-16 — — EP disclosed
US-10450417-B2 Resin, composition, cured film, method for manufacturing cured film and semiconductor device FUJIFILM CORPORATION (JP) 2019-10-22 — — US disclosed
EP-3339023-B1 LAMINATE, METHOD FOR MANUFACTURING THE LAMINATE, SEMICONDUCTOR DEVICE, AND METHOD FOR MANUFACTURING THE SEMICONDUCTOR DEVICE FUJIFILM CORP (JP) 2019-07-03 — — EP disclosed
US-20180222164-A1 LAMINATE, METHOD FOR MANUFACTURING LAMINATE, SEMICONDUCTOR DEVICE, AND METHOD FOR MANUFACTURING THE SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2018-08-09 — — US disclosed
US-20180215874-A1 RESIN, COMPOSITION, CURED FILM, METHOD FOR MANUFACTURING CURED FILM AND SEMICONDUCTOR DEVICE FUJIFILM CORPORATION (JP) 2018-08-02 — — US disclosed
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